Protein Alignment CG4630 and slc22a16

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_002936981.2
• Gene: slc22a16 / 100488673
• XenbaseID: XB-GENE-961385
• Length: 567
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 169/586 - (28%)
• Similarity: 272/586 - (46%)
• Gaps: 84/586 - (14%)

  Fly    22 IGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWVSIAVPGS 86
            :|.|||||...|.......:....:.|:.||.|.:|.:.|..||           |..|:.:|.:
 Frog     8 VGHFGRFQALIYFSSAFQAISCGIHYLASVFIAITPKFICRAPE-----------NISSVLLPNA 61

  Fly    87 WSKRGH-----FTPSTCERFVANGDHLESSSDPWSAWPLDQCF---AEN--FTTETERCNQFVYG 141
            .:.|..     :||.         |:|....:....|.|:||.   .||  :.|.:...|:.::.
 Frog    62 STLRLEDVWELWTPK---------DYLVVKQENGDIWELNQCSRFKRENTSYLTYSYDGNKTLFS 117

  Fly   142 SS----------ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFC 196
            .|          |.:||..|.|.| |..|....:......|:::|..:.|.:|||.||:.|....
 Frog   118 CSNGYYYDNTNLESSIVTDWHLVC-EREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRRLILWLT 181

  Fly   197 IVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVG 261
            .....|.|:|.|.::||.||:....|.|:.:||.|.:.|:...|.||.:.|..:|:.::.|:|||
 Frog   182 STGQFLFGIAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARSWASMHVHAFFAVG 246

  Fly   262 EALLGLSVFL-PDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRD 325
            ..::.|..|| ..|...|:.||:..|..|...|::||:..||.::.:.::...:|....|.|:
 Frog   247 VMIVSLVGFLVRTWWMYQIILSLTTLPFVLCCWMLPETPFWLYSQGKHKEVEKLIGTIEKWNK-- 309

  Fly   326 ISV-----ELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIW 385
            ||.     ||.:..:.|:.:.:|           :||.     :|.::..:.....|...:.|||
 Frog   310 ISTPCKLSELCSVQETQKTEMDT-----------LKKH-----SVLDLFYNWSFARRTVTVWLIW 358

  Fly   386 AVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVA 450
            ...::.||..:||:.:|.||:|||..|...||||.|.:|...:.:.|||..|:..|:|.::.|
 Frog   359 FTGSLGYYVFALNSVNLGGNEYLNLFLTSAVEIPSYIVACFGMDKIGRRNTLAPFLILSAVIC-- 421

  Fly   451 SGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGG 515
             |.:.|...|           ||     .:.:.:.:.||..|..:|.:||.:|||:.||::||..
 Frog   422 -GIIMLIPQD-----------HS-----TVTIAMSMGGKFSIAVAFGLIYLYTAELYPTIVRSLA 469

  Fly   516 VGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAIAL 580
            ||..|...|.|:::|||...|...:..:|.:|.|.::.:.|:|:|.||||....|..|:|||..:
 Frog   470 VGSGSMMCRIGSVVAPFCVYLTDVWIFMPQMLVGIMAFLTGVLTLKLPETLGVPLTSTIEEAAEM 534

  Fly   581 G 581
            |
 Frog   535 G 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	164/575 (29%)
slc22a16	XP_002936981.2	MFS_SLC22A16_CT2	111..517	CDD:340933	129/443 (29%)