Protein Alignment CG4630 and slc22a5

DIOPT Version :10

• Sequence 1: NP_001260948.1
• Gene: CG4630 / 36458
• FlyBaseID: FBgn0033809
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_021324939.1
• Gene: slc22a5 / 100000685
• ZFINID: ZDB-GENE-091012-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 578
• Identity: 180/578 - (31%)
• Similarity: 287/578 - (49%)
• Gaps: 75/578 - (12%)

  Fly    14 DFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANW 78
            ::|:....:|:.|.|..|.:.|:.|..:....:.|..||.|.||.:||       .||.....:|
Zfish     3 NYDEDTAFLGQTGPFFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRC-------RVDVNLTEDW 60

  Fly    79 VSIAVPGSWSKRGHFTPSTCERFVANGDHLES----SSDPWSAWPLDQCFAENFT-TETERCNQ- 137
            :..:.|......|....|.|.|:     .|::    |...:|...:      |.| ...|||..
Zfish    61 LEASAPTETLSNGDLQVSQCWRY-----SLQTLTNLSGQGYSPGQI------NITDIPRERCEDG 114

  Fly   138 FVYGSS--ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFM 200
            :||.:.  ..|||.:|.|.| ::.|::....:..:.|.::|:.:||.|:||:|||.:....:...
Zfish   115 WVYSADVYHSTIVSEWDLVC-DSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAE 178

  Fly   201 ALTGVAQAL--SWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYF--YAVG 261
            ||...||:.  ||.....|:| .:.|...| :|..||::|.|::....|.:.: .|..|  |.||
Zfish   179 ALLMFAQSFSPSWLIFCVLYF-FIGAFQIS-LYITAFVLGNEVLSGSLRVLFT-TLGAFLHYCVG 240

  Fly   262 EALLGLSVF-LPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRD 325
            ..||....| :..||.|...||...::.:..:||:|||.||||::...:::..|:|.||:.||..
Zfish   241 YMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVP 305

  Fly   326 ISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAI 390
             :.|::  |||.::.....|:..             :.|:..:..|:|....:..|||..|:| |
Zfish   306 -APEVI--FKQSQIKEAAFQKSK-------------YSALDVLRTSNIRRTTFMCLLLWMAIN-I 353

  Fly   391 VYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVT 455
            .|:|||||.|:|||:.:||..|..:.|:|.|.::...|:...||..||..|:      :..||:.
Zfish   354 GYFGLSLNTTNLSGDPFLNCFLSAVTEVPAYIVSTFLLKSCPRRPVLSAFLV------IGGGFLL 412

  Fly   456 LAQGDWIP--CQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGV 518
            |.|  .||  .||             |.:.|.:.||.|.|.||.|:|.:|||:.|||:|:.|:|:
Zfish   413 LVQ--LIPDRLQT-------------LALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGM 462

  Fly   519 MSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEE 576
            .|:.||.|::.||::..|.::...||.:|.|:|::.|.|.:|.|||||.:.||:.:|:
Zfish   463 CSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQ 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	178/564 (32%)
slc22a5	XP_021324939.1	MFS_SLC22A4_5_OCTN1_2	104..507	CDD:340934	145/444 (33%)