Protein Alignment AQP and AQP11

DIOPT Version :9

• Sequence 1: NP_523728.1
• Gene: AQP / 36456
• FlyBaseID: FBgn0033807
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_766627.1
• Gene: AQP11 / 282679
• HGNCID: 19940
• Length: 271
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 61/259 - (23%)
• Similarity: 108/259 - (41%)
• Gaps: 27/259 - (10%)

  Fly     4 TALGISALFMVGCCALAQIARVISRRLVTREGLVPI---LINEAIAAAELCACCFELIIVADNFG 65
            |:||:    |:....|..:|||::|:.:.|    |:   .:.|.:|..:||.|..||.::::...
Human    16 TSLGL----MLSVVLLMGLARVVARQQLHR----PVAHAFVLEFLATFQLCCCTHELQLLSEQHP 72

  Fly    66 V--SMYAVCLFLLTIWWGRVWGDASACPYTHMEDVVEGRTSFKEMALRSWAELMGGCCVYRVVQV 128
            .  :.....::..::..|......|:.|...|..::.|..|.:..|:|..|:|:...|.......
Human    73 AHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYCTSA 137

  Fly   129 FWWLELAETHRGRAFEACNADMQVSPYLGAVIEGVATLLCRLASKTISEKEPRFGSYIDSFIGTS 193
            .|.|.|.:.|......||...::|......:.|.|.:.|...|.....|            :.|.
Human   138 LWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSALLHFQE------------VRTK 190

  Fly   194 LVVAVYA--FNYVLLAAFNFSGGYFNPVLATALKWGCRGHTHLEHIIVYWIGACAGAVLSIPVF 255
            |.:.:.|  ..:::.|..:.:|..|||.||.:|.:.|......:..||||:....|.:|.|.:|
Human   191 LRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMILMF 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP	NP_523728.1	None
AQP11	NP_766627.1	MIP	46..257	CDD:294134	50/221 (23%)
		NPC. /evidence=ECO:0000250|UniProtKB:Q96PS8	99..101		0/1 (0%)
		NPA. /evidence=ECO:0000250|UniProtKB:Q96PS8	216..218		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158447
Domainoid	1	1.000	72	1.000	Domainoid score	I9326
eggNOG	1	0.900	-	-		E1_2A80J
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41908
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21191
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.800