Protein Alignment Orc3 and orc3

DIOPT Version :10

• Sequence 1: NP_476904.1
• Gene: Orc3 / 36454
• FlyBaseID: FBgn0005654
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_031757319.1
• Gene: orc3 / 100125181
• XenbaseID: XB-GENE-984200
• Length: 716
• Species: Xenopus tropicalis
• Alignment Length: 778
• Identity: 257/778 - (33%)
• Similarity: 389/778 - (50%)
• Gaps: 134/778 - (17%)

  Fly     4 TISVSKGCFVYKNGATRAGKKAASKRKRPAAE-----SSSLLGKEVVQQPFYEEYRKAWNQINDH 63
            |.||||||||:         |.::|:|:.:..     :..|...|..::.| |..:..|.|:...
 Frog    10 TSSVSKGCFVF---------KPSTKKKKTSLTVADYFNEGLKDSEDGKKRF-ESCQLLWQQMKSQ 64

  Fly    64 IADLQHRSYARTLEQLVDFVVGQAERDTPDE-----------VLPTAALLTGINQPDHLSQFTAL 117
            ...||.....|..|.|:.| :.::..|..|:           .:|||||:.|:|..||...|.:|
 Frog    65 TEQLQEELNKRLFENLIGF-LRKSHADFHDKKDDWSCRMRASEIPTAALVLGVNVTDHDLTFNSL 128

  Fly   118 TQRLHAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVEQMEDEDEDEDGAERDRKRLRRSQ 182
            ...||......|.:|||::|..:|..::.|:..|:.:.|::|.  ||:|::....:     |:..
 Frog   129 ADILHETITPYVVLLQSKECPGIKQLLQKLLIQLMGNTADIEL--DEEEEQVTISQ-----RKMN 186

  Fly   183 CTMKQLKSWY---TNNFDSEQKRRQ----------LVVILPDFECFNASVLQDLILILSAHCGSL 234
            |::..|..||   |....|.:|:|.          :|||..|.|.|.|||||:.|:|.|.:...|
 Frog   187 CSLASLSGWYKRATKKPASPKKKRSSTSTHWESPPVVVIFKDLESFTASVLQEFIVISSGYVQEL 251

  Fly   235 PFVLVLGVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTFKF 299
            |.|||.|:||:...:|..|.:.|||::.:.:||:.:....|..|:|::||:..:.|.|||:..:.
 Frog   252 PLVLVFGIATSPMIIHRLLSHSVSSRLCIELFQSMSCTEHLATVVDQLLLTNHFPFKLSGRALQV 316

  Fly   300 LTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSKALGRIKQLTHEDMETIRRLPSFRP 364
            |..||||:|||:..||:|.:..::|||:......||....::..|||.|:|...|.||.|.||..
 Frog   317 LITIFLYHDFSVQNFIKGLQLSVVEHFYTQPLSVLCCSLPESRKRIKNLSHAQCENIRHLSSFMS 381

  Fly   365 YVEQINDCKRIIAVLTDDDYLKKKLPQLLR-------------DCLLHFLLFRCSLEFLTELVGD 416
            |||. ...:..:.:||:|.:||:...:.|.             .||.||...
 Frog   382 YVES-QTPENQVKLLTNDSFLKEMTQEFLERLTSYHENFTPILRCLHHFTCI------------- 432

  Fly   417 LPRCPLGKLRRELYVNCLNRAIISTPEYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPL 481
            ||:.||||..||||..||.:.:..|.:|...|.:|..|:|||.|..:.:
 Frog   433 LPKYPLGKQVRELYCACLEKKVWETEDYNSALLLLRMLAKDEIVTTLQK---------------- 481

  Fly   482 ELGEACTAVLRP-----------KLEAIRLAVDEVVKATM-ATITTTSPNETRQATDHLTPVASR 534
                 |.|||.|           |||...:....:.:.|: .....|||.:..|....|
 Frog   482 -----CVAVLTPYSEKELGHTLEKLEEFLIHFQSLEENTLNGEDEDTSPQKALQKKTDL------ 535

  Fly   535 QELKDQLLQRSKEDKMRHQLNTPTTQFGRALQKTLQLIETQIVQDHLRALQDAPPIHELFVFSDI 599
            .:|:.:||: .||.:...:|    |:|....|..:..|:. ||:::| ...:..|:||:..||..
 Frog   536 YQLQKKLLE-MKETRRAKKL----TKFEMLRQDVVDFIDC-IVREYL-VPPEMLPLHEVVYFSAA 593

  Fly   600 ATVRRNIIGAPRAALHTALNNPHFYMQCKCCELQDQSLLVGTL-PDLSVVYKLHLECGRMINLFD 663
            :|:||::..|||.|||||||||..|::    .|::::..|..: ||:.:.|||||||||:|||:|
 Frog   594 STLRRHLNAAPRVALHTALNNPASYLK----TLENEAGSVSNVAPDICIAYKLHLECGRLINLYD 654

  Fly   664 WLQAFRSVV-----SDSDHEEVAQEQIDPQIQARFTRAVAELQFLGYIKMSKRKTDHATRLTW 721
            ||:||.:||     ||||    :.:|:|....|||.|||:||:.||::|.:|:||||..||||
 Frog   655 WLEAFSTVVHAGEGSDSD----SAQQVDEVTHARFIRAVSELELLGFVKPTKQKTDHVARLTW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc3	NP_476904.1	ORC3_N	26..334	CDD:462070	103/336 (31%)
		ORC3_ins	345..597	CDD:466140	74/276 (27%)
		Orc3	<589..721	CDD:412052	68/137 (50%)
orc3	XP_031757319.1	ORC3_N	31..351	CDD:462070	101/328 (31%)
		ORC3_ins	362..594	CDD:466140	76/279 (27%)
		ORC_WH_C	605..713	CDD:436299	58/115 (50%)