Protein Alignment Spt-I and LCB1

DIOPT Version :9

• Sequence 1: NP_610842.1
• Gene: Spt-I / 36448
• FlyBaseID: FBgn0086532
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_014025.1
• Gene: LCB1 / 855342
• SGDID: S000004911
• Length: 558
• Species: Saccharomyces cerevisiae
• Alignment Length: 480
• Identity: 161/480 - (33%)
• Similarity: 239/480 - (49%)
• Gaps: 68/480 - (14%)

  Fly    44 RRRQLTKEEEDRIIADYEPEPLV--ADTDPNHPLLHTRVVQSRVGKRIQVDGH------------ 94
            ::..|:.:|.|.:|.|:||||||  :.||..    ..||.::.|...:.:..|
Yeast    84 QKPNLSPQEIDALIEDWEPEPLVDPSATDEQ----SWRVAKTPVTMEMPIQNHITITRNNLQEKY 144

  Fly    95 -DCLNLGSHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAI 158
             :..||.|:|:|.....:.:.|....:::.||||:|||.||||..|||..||..:|:|.|.:.::
Yeast   145 TNVFNLASNNFLQLSATEPVKEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQGSV 209

  Fly   159 VYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERL---LIEQ 220
            :|...|....|.:||:.||||:|..|:.|:..:|..|..||||:.:|.|||:..||.|   |.||
Yeast   210 LYGQDFCAAPSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLECLLNELTEQ 274

  Fly   221 EKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGV 285
            ||.:    |..|..|:|:|.|||:.|:|::.|||:|..|:.|||.|||:||:.|.|.||..|.|:
Yeast   275 EKLE----KLPAIPRKFIVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVDETFSIGVLGATGRGL 335

  Fly   286 TEHFNVDR-DEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISAL 349
            :||||:|| ..:|:....|..::.:.|||.:|...:..|||:....|.|||.||.....:....|
Yeast   336 SEHFNMDRATAIDITVGSMATALGSTGGFVLGDSVMCLHQRIGSNAYCFSACLPAYTVTSVSKVL 400

  Fly   350 DRFEREPQIFEQLQAKSKTLHQKF-----LRFSKLTLRGDEVSPVKHLYLAQPA----------- 398
            ...:......:.||..||:||..|     || |.:.:....||.|.||.|. ||
Yeast   401 KLMDSNNDAVQTLQKLSKSLHDSFASDDSLR-SYVIVTSSPVSAVLHLQLT-PAYRSRKFGYTCE 463

  Fly   399 -------------------ENFDKELKLLTELADKCIAR-GVAVVQAAYLQNRERQPVRPSIRIA 443
                               |.:::|.|.|..:.|..:.. .|.:.:...:..:|..|:.||::|.
Yeast   464 QLFETMSALQKKSQTNKFIEPYEEEEKFLQSIVDHALINYNVLITRNTIVLKQETLPIVPSLKIC 528

  Fly   444 VNRLLESSEIDNAFEVIESVSSSVL 468
            .|..:...|:.||   .|||..|:|
Yeast   529 CNAAMSPEELKNA---CESVKQSIL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt-I	NP_610842.1	AAT_I	22..468	CDD:302748	160/478 (33%)
		BioF	79..463	CDD:223234	144/436 (33%)
LCB1	NP_014025.1	AAT_I	62..547	CDD:418510	159/475 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343895
Domainoid	1	1.000	236	1.000	Domainoid score	I384
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4681
Inparanoid	1	1.050	252	1.000	Inparanoid score	I658
Isobase	1	0.950	-	0	Normalized mean entropy	S1053
OMA	1	1.010	-	-		QHG54231
OrthoFinder	1	1.000	-	-		FOG0004733
OrthoInspector	1	1.000	-	-		oto99117
orthoMCL	1	0.900	-	-		OOG6_102559
Panther	1	1.100	-	-	LDO	PTHR13693
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R651
SonicParanoid	1	1.000	-	-		X3331
TreeFam	1	0.960	-	-
	16	15.740