DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spt-I and LCB1

DIOPT Version :9

Sequence 1:	NP_610842.1	Gene:	Spt-I / 36448	FlyBaseID:	FBgn0086532	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001031796.1	Gene:	LCB1 / 829800	AraportID:	AT4G36480	Length:	482	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	185/484 - (38%)
Similarity:	292/484 - (60%)	Gaps:	29/484 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IQLFNEI---GSIFRNTPTFALVL-----------ETLLLITVIWLLLHRRGGGRRRQLTKEEED 54
            :::||..   .::...:|:..:||           |.||.:.:|.||..:.....:|.||::|.|
plant     6 VEMFNAALNWVTMILESPSARVVLFGVPIRGHFFVEGLLGVVIIILLTRKSYKPPKRPLTEQEID 70

  Fly    55 RIIADYEPEPLV--ADTDPNHPLLHTRVVQSRVGKRIQVDGHDCLNLGSHNYLGFLEDQEILEEA 117
            .:..::.||||:  ...|..|   ...|::|..|....|:|.|.:|..|.||||.:..:::||..
plant    71 ELCDEWVPEPLIPPITEDMKH---EPPVLESAAGPHTTVNGKDVVNFASANYLGLIGHEKLLESC 132

  Fly   118 CKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKRGDLIF 182
            ..:|.|||||||||||||||:|||||.|.||:||:|..::|:||||.||:.|.||.:.|:||:|.
plant   133 TSALEKYGVGSCGPRGFYGTIDVHLDCETRISKFLGTPDSILYSYGLSTMFSTIPCFCKKGDVIV 197

  Fly   183 VDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNT 247
            .||.|::.||.||..||||||:|||||:|.| |:.:|:.....|..|   ..||::|||.:|.|:
plant   198 ADEGVHWGIQNGLQLSRSTIVYFKHNDMESL-RITLEKIMTKYKRSK---NLRRYIVAEAVYQNS 258

  Fly   248 GEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGG 312
            |:|.||.::|.|::||:.|:.:|||.|||.||:.|.|:.||.:|..:::|:::|.|..::||.||
plant   259 GQIAPLDEIVKLKEKYRFRVILDESNSFGVLGRSGRGLAEHHSVPIEKIDVVTAAMGHALATEGG 323

  Fly   313 FCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRFEREPQIFEQLQAKSKTLHQKFLRFS 377
            ||.|:..|.::||||..||:|||||||.|..|||:|:|..::.|.:..:|:.....|.:......
plant   324 FCTGNARIIDYQRLSSSGYVFSASLPPYLASAAITAIDVIDQNPDMLVKLKQNVALLWKGLSDIK 388

  Fly   378 KLTLRGDEVSPVKHLYLAQPAENFDKELKLLTELADKCIARGVAVV---QAAYLQNRERQPVRPS 439
            .::|..:..||:..|.|.:.:.:...:|.||.::||:.:.....:|   :.::| ::.|.||  .
plant   389 GMSLTSNRESPIVFLKLEKSSGSAKDDLLLLEKMADRALKEDSLLVVSSKRSFL-DKCRLPV--G 450

  Fly   440 IRIAVNRLLESSEIDNAFEVIESVSSSVL 468
            |::.|:.....|::..|.|.::.::|.:|
plant   451 IKLYVSAGHSESDLLKASESLKRLASELL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spt-I	NP_610842.1	AAT_I	22..468	CDD:302748	181/461 (39%)
Spt-I	NP_610842.1	BioF	79..463	CDD:223234	161/386 (42%)
LCB1	NP_001031796.1	PLN02822	1..481	CDD:178417	185/484 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	296	1.000	Domainoid score	I345
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4681
Inparanoid	1	1.050	326	1.000	Inparanoid score	I689
OMA	1	1.010	-	-		QHG54231
OrthoDB	1	1.010	-	-		D438936at2759
OrthoFinder	1	1.000	-	-		FOG0004733
OrthoInspector	1	1.000	-	-		oto4021
orthoMCL	1	0.900	-	-		OOG6_102559
Panther	1	1.100	-	-	LDO	PTHR13693
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3331
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840