Protein Alignment Spt-I and Alas2

DIOPT Version :10

• Sequence 1: NP_610842.1
• Gene: Spt-I / 36448
• FlyBaseID: FBgn0086532
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_038955432.1
• Gene: Alas2 / 25748
• RGDID: 2084
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 345
• Identity: 93/345 - (26%)
• Similarity: 161/345 - (46%)
• Gaps: 37/345 - (10%)

  Fly    91 VDGHDCLNLGSHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLE 155
            :|..|.....|::|||......:|:...::|:.:|.|:.|.|...||...|::||..:|:....:
  Rat   192 MDSKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHHKD 256

  Fly   156 EAIVYSYGF-------STVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDL 213
            .|:::|..|       .|:|..:|     |..|:.|...:.::.:|:..|.:....|:|||...|
  Rat   257 SALLFSSCFVANDSTLFTLAKLLP-----GCEIYSDAGNHASMIQGIRNSGAVKFVFRHNDPGHL 316

  Fly   214 ERLLIEQEKRDQKNPKKAAKTRRFLVA-EGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGT 277
            ::||   ||.|.|.||        :|| |.::...|.||||.:|..:..:|....|:||..:.|.
  Rat   317 KKLL---EKSDPKTPK--------IVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGL 370

  Fly   278 LGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLT 342
            .|..|.|:.|...: ..::|:||..:..:...|||:...:..:.:..|....|:||:.|||||:.
  Rat   371 YGTRGAGIGERDGI-MHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVL 434

  Fly   343 QAAISALDRFEREPQIFEQLQAKSKTLHQKFLRFSKLTL--RGDEVSPVKHLYLAQPAENFDKEL 405
            ..|:.::...:.     |:.||..:. ||:.::..:..|  ||..|.|.....:.....|    .
  Rat   435 SGALESVRLLKG-----EEGQALRRA-HQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGN----A 489

  Fly   406 KLLTELADKCIARGVAVVQA 425
            .|.:::.|..:|:....|||
  Rat   490 ALNSKICDLLLAKHSIYVQA 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt-I	NP_610842.1	AAT_I	22..468	CDD:450240	93/345 (27%)
Alas2	XP_038955432.1	Preseq_ALAS	5..100	CDD:462658
		5aminolev_synth	149..554	CDD:273820	93/345 (27%)