Protein Alignment Spt-I and ALAS1

DIOPT Version :9

• Sequence 1: NP_610842.1
• Gene: Spt-I / 36448
• FlyBaseID: FBgn0086532
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001291373.1
• Gene: ALAS1 / 211
• HGNCID: 396
• Length: 657
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 101/376 - (26%)
• Similarity: 168/376 - (44%)
• Gaps: 59/376 - (15%)

  Fly    77 HTRVVQSRVGKRIQV-----DGHDCLNLG-------SHNYLGFLEDQEILEEACKSLRKYGVGSC 129
            ||..|...|.:|..:     |..|.|...       |::|||......:......:|:::|.|:.
Human   231 HTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAG 295

  Fly   130 GPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKR--GDLIFVDEAVNFAIQ 192
            |.|...||...|:|||..:|...|.:.|:::|..|....|.:...||.  |..|:.|...:.::.
Human   296 GTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMI 360

  Fly   193 KGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVA-EGIYMNTGEICPLPDL 256
            :|:..||.....|:||||..|..||   ::.|...||        :|| |.::...|.:|||.:|
Human   361 QGIRNSRVPKYIFRHNDVSHLRELL---QRSDPSVPK--------IVAFETVHSMDGAVCPLEEL 414

  Fly   257 VALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRD----EVDLISAGMEGSMATVGGFCVGS 317
            ..:..::....|:||..:.|..|..|.|:.     |||    ::|:||..:..:...|||:...:
Human   415 CDVAHEFGAITFVDEVHAVGLYGARGGGIG-----DRDGVMPKMDIISGTLGKAFGCVGGYIAST 474

  Fly   318 HFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRFEREPQIFEQLQAK-SKTLHQKFLRFSKLTL 381
            ..:.:..|....|:||:.||||||...|:.::       :|.:..:.: .:..||:.::..:..|
Human   475 SSLIDTVRSYAAGFIFTTSLPPMLLAGALESV-------RILKSAEGRVLRRQHQRNVKLMRQML 532

  Fly   382 RGDEVSPVKH-------LYLAQPAENFDKELKLLTELADKCIARGVAVVQA 425
            . |...||.|       :.:|..|:|        ||:.|:.::|....|||
Human   533 M-DAGLPVVHCPSHIIPVRVADAAKN--------TEVCDELMSRHNIYVQA 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt-I	NP_610842.1	AAT_I	22..468	CDD:302748	101/376 (27%)
		BioF	79..463	CDD:223234	99/374 (26%)
ALAS1	NP_001291373.1	Preseq_ALAS	19..154	CDD:286162
		AAT_I	214..619	CDD:302748	101/376 (27%)
		BioF	214..605	CDD:223234	101/376 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910