Protein Alignment Spt-I and Sptlc2

DIOPT Version :9

• Sequence 1: NP_610842.1
• Gene: Spt-I / 36448
• FlyBaseID: FBgn0086532
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_035609.1
• Gene: Sptlc2 / 20773
• MGIID: 108074
• Length: 560
• Species: Mus musculus
• Alignment Length: 506
• Identity: 137/506 - (27%)
• Similarity: 233/506 - (46%)
• Gaps: 82/506 - (16%)

  Fly     7 FNEIGSIFRNTPTFALVLETLLLITVIWLLLHRRGGGRRRQLTK-------EEEDRIIADYEPEP 64
            |||   .|..||....|| |.:...|:.|..:.|...|..::.|       ||:...::.|:
Mouse    57 FNE---AFEETPMLVAVL-TYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQ--- 114

  Fly    65 LVADTDPNHPLLHTRVVQSRV------------GKRIQV---DGHD--------------CLNLG 100
                   :....:||.:..|:            |.::.:   ..||              .:|:|
Mouse   115 -------DFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMG 172

  Fly   101 SHNYLGFLEDQEILEE-ACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGF 164
            |:|||||..:....:| |.:.|::||.|.|..|...|.:|.|.:||..:|:|:|:|.|:.|..||
Mouse   173 SYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGF 237

  Fly   165 STVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPK 229
            :|.:..|||...:|.||..||..:.::..|...|.:||..||||:::.||:||.:.....|...:
Mouse   238 ATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTR 302

  Fly   230 KAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRD 294
            :..| :..::.||||...|.|..||:::||::|||..|::||:.|.|.||..|.||.::|.:|.:
Mouse   303 RPWK-KILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPE 366

  Fly   295 EVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISAL------DRFE 353
            :||::......|....||:..|...:.::.|......:::.|:.|.:.:..|:::      |...
Mouse   367 DVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTS 431

  Fly   354 REPQIFEQLQAKSKTLHQKFLRFSKLTLRGDEVSPVKHLYLAQPAE--NFDKELKLLTELADKCI 416
            ...:..:|| |::....::.|:.....:.|:|.|||..|.|..||:  .|.:|:          :
Mouse   432 LGKECIQQL-AENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREM----------L 485

  Fly   417 ARGVAVVQAAYLQNRERQPVRPSIRIAVNRLLESSE----IDNAFEVIESV 463
            .|.:.||...:       |..|.|.......|.::.    :|.|.:.|:.|
Mouse   486 KRNIGVVVVGF-------PATPIIESRARFCLSAAHTKEILDTALKEIDEV 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt-I	NP_610842.1	AAT_I	22..468	CDD:302748	131/491 (27%)
		BioF	79..463	CDD:223234	118/425 (28%)
Sptlc2	NP_035609.1	PLN02483	65..540	CDD:178101	132/495 (27%)
		BioF	115..530	CDD:223234	120/434 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312139at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820