Protein Alignment Spt-I and Alas2

DIOPT Version :10

• Sequence 1: NP_610842.1
• Gene: Spt-I / 36448
• FlyBaseID: FBgn0086532
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001396401.1
• Gene: Alas2 / 11656
• MGIID: 87990
• Length: 600
• Species: Mus musculus
• Alignment Length: 376
• Identity: 97/376 - (25%)
• Similarity: 165/376 - (43%)
• Gaps: 77/376 - (20%)

  Fly   101 SHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGF- 164
            |::|||......:|:...::|:.:|.|:.|.|...||...|::||..:|:....:.|:::|..|
Mouse   209 SNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFV 273

  Fly   165 ------STVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKR 223
                  .|:|..:|     |..|:.|...:.::.:|:..|.:....|:|||...|::||   ||.
Mouse   274 ANDSTLFTLAKLLP-----GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLL---EKS 330

  Fly   224 DQKNPKKAAKTRRFLVA-EGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTE 287
            |.|.||        :|| |.::...|.||||.:|..:..:|....|:||..:.|..|..|.|:.|
Mouse   331 DPKTPK--------IVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGE 387

  Fly   288 HFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRF 352
            ...: ..::|:||..:..:...|||:...:..:.:..|....|:||:.|||||:...|:.::...
Mouse   388 RDGI-MHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLL 451

  Fly   353 ERE------------------------------PQIFEQLQAKSKTLHQKF--LRFSKLTL---- 381
            :.|                              |.....::..:..|:.|.  |..||.::
Mouse   452 KGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLSKHSIYVQA 516

  Fly   382 -------RGDE---VSPVKHLYLAQPAENFDKELKLL-TE----LADKCIA 417
                   ||:|   ::|..| :..|..|||.::|.|. ||    |.|..:|
Mouse   517 INYPTVPRGEELLRLAPSPH-HSPQMMENFVEKLLLAWTEVGLPLQDVSVA 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt-I	NP_610842.1	AAT_I	22..468	CDD:450240	97/376 (26%)
Alas2	NP_001396401.1	Preseq_ALAS	18..113	CDD:462658
		5aminolev_synth	156..561	CDD:273820	94/369 (25%)