DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spt-I and Alas2

DIOPT Version :9

Sequence 1:NP_610842.1 Gene:Spt-I / 36448 FlyBaseID:FBgn0086532 Length:468 Species:Drosophila melanogaster
Sequence 2:XP_030107059.1 Gene:Alas2 / 11656 MGIID:87990 Length:600 Species:Mus musculus


Alignment Length:376 Identity:97/376 - (25%)
Similarity:165/376 - (43%) Gaps:77/376 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   101 SHNYLGFLEDQEILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGF- 164
            |::|||......:|:...::|:.:|.|:.|.|...||...|::||..:|:....:.|:::|..| 
Mouse   209 SNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFV 273

  Fly   165 ------STVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKR 223
                  .|:|..:|     |..|:.|...:.::.:|:..|.:....|:|||...|::||   ||.
Mouse   274 ANDSTLFTLAKLLP-----GCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLL---EKS 330

  Fly   224 DQKNPKKAAKTRRFLVA-EGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTE 287
            |.|.||        :|| |.::...|.||||.:|..:..:|....|:||..:.|..|..|.|:.|
Mouse   331 DPKTPK--------IVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGE 387

  Fly   288 HFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRF 352
            ...: ..::|:||..:..:...|||:...:..:.:..|....|:||:.|||||:...|:.::...
Mouse   388 RDGI-MHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLL 451

  Fly   353 ERE------------------------------PQIFEQLQAKSKTLHQKF--LRFSKLTL---- 381
            :.|                              |.....::..:..|:.|.  |..||.::    
Mouse   452 KGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLSKHSIYVQA 516

  Fly   382 -------RGDE---VSPVKHLYLAQPAENFDKELKLL-TE----LADKCIA 417
                   ||:|   ::|..| :..|..|||.::|.|. ||    |.|..:|
Mouse   517 INYPTVPRGEELLRLAPSPH-HSPQMMENFVEKLLLAWTEVGLPLQDVSVA 566

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spt-INP_610842.1 AAT_I 22..468 CDD:302748 97/376 (26%)
BioF 79..463 CDD:223234 97/376 (26%)
Alas2XP_030107059.1 Preseq_ALAS 18..113 CDD:370250
5aminolev_synth 156..561 CDD:273820 94/369 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0156
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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