DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrk and CRK3

DIOPT Version :9

Sequence 1:	NP_477255.1	Gene:	Nrk / 36445	FlyBaseID:	FBgn0020391	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_177210.1	Gene:	CRK3 / 843390	AraportID:	AT1G70530	Length:	646	Species:	Arabidopsis thaliana

Alignment Length:	345	Identity:	82/345 - (23%)
Similarity:	147/345 - (42%)	Gaps:	78/345 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   379 NTSRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVY 443
            |:...|..|||..|.|   |.|   ..:.|:.||...:.:.:.....|.:|:.::.:...|.:..
plant   244 NSGNSTSDGNGGHNHL---GVI---LAVTSSVVAFVLLVSAAGFLLKKRHAKKQREKKQLGSLFM 302

  Fly   444 V-----------------------RSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQM 485
            :                       ..||||..|.|::    |::.:.:  .||||.|..: :.|.
plant   303 LANKSNLCFSYENLERATDYFSDKNKLGQGGSGSVYK----GVLTNGK--TVAVKRLFFN-TKQW 360

  Fly   486 QMDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRL 550
            ...|..|..|:::.||.|:|:|||....|....|::||:|...|.::|..          .:|..
plant   361 VDHFFNEVNLISQVDHKNLVKLLGCSITGPESLLVYEYIANQSLHDYLFV----------RKDVQ 415

  Fly   551 QLNELHLLQMAANIAAGMLYLSER---KFVHRDLATRNCLINEHMAVKIADFGLSH-----KIYL 607
            .||.....::....|.||.||.|.   :.:|||:...|.|:.:....:||||||:.     |.::
plant   416 PLNWAKRFKIILGTAEGMAYLHEESNLRIIHRDIKLSNILLEDDFTPRIADFGLARLFPEDKTHI 480

  Fly   608 QDYYKGDENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKE 672
            .....|      .:.:|..|.::..|.:.::||:::|:.:.||          :|.:....::::
plant   481 STAIAG------TLGYMAPEYVVRGKLTEKADVYSFGVLMIEV----------ITGKRNNAFVQD 529

  Fly   673 -GNVLGCPDNTPLSVYALMR 691
             |::|       .||::|.|
plant   530 AGSIL-------QSVWSLYR 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308
		KR	217..299	CDD:214527
		PTKc_Musk	435..713	CDD:133181	68/289 (24%)
		Pkinase_Tyr	441..707	CDD:285015	67/283 (24%)
CRK3	NP_177210.1	Stress-antifung	30..127	CDD:396296
		Stress-antifung	157..237	CDD:396296
		STKc_IRAK	329..593	CDD:270968	67/254 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050