DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Nrk and GSO2

DIOPT Version :9

Sequence 1:NP_477255.1 Gene:Nrk / 36445 FlyBaseID:FBgn0020391 Length:724 Species:Drosophila melanogaster
Sequence 2:NP_199283.1 Gene:GSO2 / 834499 AraportID:AT5G44700 Length:1252 Species:Arabidopsis thaliana


Alignment Length:454 Identity:97/454 - (21%)
Similarity:181/454 - (39%) Gaps:108/454 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   288 RWQHCDIPMCPDYVDPNAVDLNTPI--------KMEKFFTPSMIFLLAGIGFVAIVTLHLMILLV 344
            |||       .|....||....:|:        |.::..:|..:.:::.|..:|.:.|.::::::
plant   839 RWQ-------ADAFVGNAGLCGSPLSHCNRAGSKNQRSLSPKTVVIISAISSLAAIALMVLVIIL 896

  Fly   345 YKLSKHKDYSQPAGAATAECSVSMRGGGDC-GGNLNTSRETLGGNGNTNTLAKWGTIRSTATIHS 408
            :....|..:.:            :|||... ..|.::|:..|..||...:..||..|        
plant   897 FFKQNHDLFKK------------VRGGNSAFSSNSSSSQAPLFSNGGAKSDIKWDDI-------- 941

  Fly   409 NCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVA 473
                                  :|...|...:.:    :|.|..|:|::|.    :.:.|.:.|.
plant   942 ----------------------MEATHYLNEEFM----IGSGGSGKVYKAE----LKNGETIAVK 976

  Fly   474 VKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVC---ALGRPMCLLFEYMAPGDLSEFLRA 535
            ..:.|||.  .....|.||...|....|.::|:|:|.|   |.|..: |::||||.|.:.::|.|
plant   977 KILWKDDL--MSNKSFNREVKTLGTIRHRHLVKLMGYCSSKADGLNL-LIYEYMANGSVWDWLHA 1038

  Fly   536 CSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYL---SERKFVHRDLATRNCLINEHMAVKIA 597
                   ...|:.:..|.....|::|..:|.|:.||   .....||||:.:.|.|::.::...:.
plant  1039 -------NENTKKKEVLGWETRLKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLDSNIEAHLG 1096

  Fly   598 DFGLSHKIYLQDYYKGDENDFI---PIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYF 659
            ||||: ||...:|....|::.:   ...::..|.....|.:.:|||::.||.|.|:.: ...|..
plant  1097 DFGLA-KILTGNYDTNTESNTMFAGSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVT-GKMPTE 1159

  Fly   660 GLTHEE--VIKYIKE-------------------GNVLGCPDNTPLSVYALMRRCWNRKPSERP 702
            .:..||  ::::::.                   .::|.|.:.....|..:..:|....|.|||
plant  1160 AMFDEETDMVRWVETVLDTPPGSEAREKLIDSELKSLLPCEEEAAYQVLEIALQCTKSYPQERP 1223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NrkNP_477255.1 CRD_FZ 67..212 CDD:295308
KR 217..299 CDD:214527 3/10 (30%)
PTKc_Musk 435..713 CDD:133181 72/298 (24%)
Pkinase_Tyr 441..707 CDD:285015 71/292 (24%)
GSO2NP_199283.1 LRRNT_2 28..68 CDD:285463
leucine-rich repeat 76..96 CDD:275380
LRR_RI 135..406 CDD:238064
LRR_8 145..204 CDD:290566
leucine-rich repeat 146..169 CDD:275380
leucine-rich repeat 170..193 CDD:275380
leucine-rich repeat 194..241 CDD:275380
LRR_8 240..300 CDD:290566
leucine-rich repeat 242..265 CDD:275380
leucine-rich repeat 266..289 CDD:275380
PLN00113 285..1232 CDD:215061 97/454 (21%)
leucine-rich repeat 290..313 CDD:275380
leucine-rich repeat 314..338 CDD:275380
leucine-rich repeat 339..362 CDD:275380
leucine-rich repeat 363..386 CDD:275380
leucine-rich repeat 387..410 CDD:275380
leucine-rich repeat 411..434 CDD:275380
leucine-rich repeat 435..458 CDD:275380
leucine-rich repeat 459..482 CDD:275380
leucine-rich repeat 483..506 CDD:275380
leucine-rich repeat 507..528 CDD:275380
leucine-rich repeat 531..554 CDD:275380
leucine-rich repeat 555..571 CDD:275380
LRR_RI 603..843 CDD:238064 3/10 (30%)
leucine-rich repeat 604..625 CDD:275380
leucine-rich repeat 626..649 CDD:275380
leucine-rich repeat 650..673 CDD:275380
leucine-rich repeat 674..697 CDD:275380
leucine-rich repeat 698..721 CDD:275380
leucine-rich repeat 722..745 CDD:275380
leucine-rich repeat 746..769 CDD:275380
leucine-rich repeat 770..794 CDD:275380
leucine-rich repeat 795..818 CDD:275380
leucine-rich repeat 819..839 CDD:275380 97/454 (21%)
STKc_IRAK 954..1232 CDD:270968 71/286 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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