DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nrk and AT5G24080

DIOPT Version :9

Sequence 1:	NP_477255.1	Gene:	Nrk / 36445	FlyBaseID:	FBgn0020391	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_001330805.1	Gene:	AT5G24080 / 832473	AraportID:	AT5G24080	Length:	872	Species:	Arabidopsis thaliana

Alignment Length:	771	Identity:	144/771 - (18%)
Similarity:	245/771 - (31%)	Gaps:	301/771 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 HANSLNAIEEPVTRRHHQRHHEREREENGYCAPYSGKVCKEYLTGQVWYSLEDPTGGWKNEQVTT 104
            ::::|...:.||.||       ...|.||....|.                      |.|:...:
plant   261 NSSNLGLTKNPVLRR-------LVLENNGNLRLYR----------------------WDNDMNGS 296

  Fly   105 ALWD---ELIS---DLTGLCREAAEKMLCAYAFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDW 163
            :.|.   ..:|   |:.|:|....           |:::..:.....||
plant   297 SQWVPEWAAVSNPCDIAGICGNGV-----------CNLDRTKKNADCLC---------------- 334

  Fly   164 VLIEEKKERNMFIKSRGHFRLPNCSSLP-HYNASMRRPNCSYIGLTELKESEVSYDCRNGNGRFY 227
                                ||....|| ..||.:...|.|   |.:..||.:     |.||.|.
plant   335 --------------------LPGSVKLPDQENAKLCSDNSS---LVQECESNI-----NRNGSFK 371

  Fly   228 MGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFHQLLEGENY----------CRNA----GGEEPHP 278
            :.|:.           :|.|   :|....|...:.:..|.          |:..    |.::..|
plant   372 ISTVQ-----------ETNY---YFSERSVIENISDISNVRKCGEMCLSDCKCVASVYGLDDEKP 422

  Fly   279 WCYTVDESVRWQHCDIPMCPDYVDPNAVDL------NTPIKMEKF--FTPSMIFLLAGIGFVAIV 335
            :|:.: :|:.:.....|....:|...|.:.      |...|..|.  ....::.:...:|.:.:|
plant   423 YCWIL-KSLNFGGFRDPGSTLFVKTRANESYPSNSNNNDSKSRKSHGLRQKVLVIPIVVGMLVLV 486

  Fly   336 TLHLMILLVYKLSKHKDYSQPAGAATAEC----SVSMRGGGDCGGNLNTSRETLGGNGNTNTLAK 396
            .| |.:||.|.|.:.:...:.|..:...|    |.:.|...:|..|
plant   487 AL-LGMLLYYNLDRKRTLKRAAKNSLILCDSPVSFTYRDLQNCTNN------------------- 531

  Fly   397 WGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAP 461
                                                          :.:.||.|.||.|::....
plant   532 ----------------------------------------------FSQLLGSGGFGTVYKGTVA 550

  Fly   462 GLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAP 526
            |      :.|||||.| |.|....:.:|..|...:....|.|:|||.|.|:......|::|||..
plant   551 G------ETLVAVKRL-DRALSHGEREFITEVNTIGSMHHMNLVRLCGYCSEDSHRLLVYEYMIN 608

  Fly   527 GDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYLSER---KFVHRDLATRNCLI 588
            |.|.:::     :::.|...    .|:.....::|...|.|:.|..|:   :.:|.|:...|.|:
plant   609 GSLDKWI-----FSSEQTAN----LLDWRTRFEIAVATAQGIAYFHEQCRNRIIHCDIKPENILL 664

  Fly   589 NEHMAVKIADFGL--------SHKIYLQDYYKGDENDFIPIRWMPLESILYNKFSLESDVWAYGI 645
            :::...|::||||        ||.:.:   .:|......| .|:....|     ::::||::||:
plant   665 DDNFCPKVSDFGLAKMMGREHSHVVTM---IRGTRGYLAP-EWVSNRPI-----TVKADVYSYGM 720

  Fly   646 CLWEV--------FSFALQPYF-------GLTH-----------------EEVIKYIK------- 671
            .|.|:        .|:..:.:|       .||:                 |||:|.:|
plant   721 LLLEIVGGRRNLDMSYDAEDFFYPGWAYKELTNGTSLKAVDKRLQGVAEEEEVVKALKVAFWCIQ 785

  Fly   672 --------EGNVL----GCPDNTPL----------------SVYALMRRCWNRKPS 699
                    .|.|:    |..|...|                .||..|||.:|.:.|
plant   786 DEVSMRPSMGEVVKLLEGTSDEINLPPMPQTILELIEEGLEDVYRAMRREFNNQLS 841

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308	22/151 (15%)
		KR	217..299	CDD:214527	16/95 (17%)
		PTKc_Musk	435..713	CDD:133181	79/343 (23%)
		Pkinase_Tyr	441..707	CDD:285015	79/337 (23%)
AT5G24080	NP_001330805.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050