DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrk and CRK23

DIOPT Version :9

Sequence 1:	NP_477255.1	Gene:	Nrk / 36445	FlyBaseID:	FBgn0020391	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_194062.1	Gene:	CRK23 / 828430	AraportID:	AT4G23310	Length:	830	Species:	Arabidopsis thaliana

Alignment Length:	342	Identity:	91/342 - (26%)
Similarity:	151/342 - (44%)	Gaps:	75/342 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 SMIFLLAGIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTSR--- 382
            |.:.::|.:  |:|..|.|:.:.|:.: :.|...:..||...               ||..|
plant   429 SSVIIIAVV--VSITALLLLFVAVFSV-RTKRRKKMIGAIPL---------------LNVKRKDT 475

  Fly   383 ---ETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYV 444
               |.|..||::.|.|        .::..:..|:...||                     :.:.:
plant   476 EVTEPLAENGDSITTA--------GSLQFDFKAIVAATN---------------------NFLPI 511

  Fly   445 RSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLG 509
            ..||||.||.|::...|..|.      ||||.| ...|.|.:.:||.|..::|:..|.|:|||||
plant   512 NKLGQGGFGEVYKGTFPSGVQ------VAVKRL-SKTSGQGEREFENEVVVVAKLQHRNLVRLLG 569

  Fly   510 VCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYL--- 571
            .|..|....|::|::....|..||          ..|..:.||:.....::...||.|:|||
plant   570 YCLEGEEKILVYEFVHNKSLDYFL----------FDTTMKRQLDWTRRYKIIGGIARGILYLHQD 624

  Fly   572 SERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFI-PIRWMPLESILYNKFS 635
            |....:||||...|.|::..|..|:||||:: :|:..|..:.:....: ...:|..|..:|.:||
plant   625 SRLTIIHRDLKAGNILLDADMNPKVADFGMA-RIFGMDQTEANTRRVVGTYGYMAPEYAMYGQFS 688

  Fly   636 LESDVWAYGICLWEVFS 652
            ::|||:::|:.::|:.|
plant   689 MKSDVYSFGVLVFEIIS 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308
		KR	217..299	CDD:214527
		PTKc_Musk	435..713	CDD:133181	69/222 (31%)
		Pkinase_Tyr	441..707	CDD:285015	69/216 (32%)
CRK23	NP_194062.1	Stress-antifung	33..129	CDD:279926
		Stress-antifung	145..240	CDD:279926
		Stress-antifung	258..350	CDD:279926
		TyrKc	511..780	CDD:197581	69/213 (32%)
		STKc_IRAK	514..781	CDD:270968	69/210 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050