DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrk and CRK40

DIOPT Version :9

Sequence 1:	NP_477255.1	Gene:	Nrk / 36445	FlyBaseID:	FBgn0020391	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_192366.1	Gene:	CRK40 / 825789	AraportID:	AT4G04570	Length:	654	Species:	Arabidopsis thaliana

Alignment Length:	413	Identity:	106/413 - (25%)
Similarity:	164/413 - (39%)	Gaps:	118/413 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 ENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNT--------PIKMEKFFTPS 321
            ::|....||....|.||     .||   |:     |...||.|..|        |...||   .|
plant   226 KDYMGRKGGMASLPSCY-----FRW---DL-----YSFHNAFDNVTRVPAPPPRPHAQEK---ES 274

  Fly   322 MIFLLAG--IGF---VAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTS 381
            .|.:..|  ||:   :|||.:...|.|:..:...|.|::                   .|.||
plant   275 CITVKKGKSIGYGGIIAIVVVFTFINLLVFIGFIKVYAR-------------------RGKLN-- 318

  Fly   382 RETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYV-- 444
                                                ||..|:.:..:.:. .|.:..|.||..
plant   319 ------------------------------------NVGSAEYSDSDGQF-MLRFDLGMIVMATD 346

  Fly   445 -----RSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNI 504
                 .:||||.||.|::    |..|:.::  ||||.| ...|.|..|:|:.|..||....|.|:
plant   347 DFSSENTLGQGGFGTVYK----GTFPNGQE--VAVKRL-TKGSGQGDMEFKNEVSLLTRLQHKNL 404

  Fly   505 VRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHL-LQMAANIAAGM 568
            |:|||.|..|....|::|::....|..|:.           .:|:..|....: .::...||.|:
plant   405 VKLLGFCNEGDEEILVYEFVPNSSLDHFIF-----------DEDKRSLLTWEVRFRIIEGIARGL 458

  Fly   569 LYL---SERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIR-WMPLESI 629
            |||   |:.|.:||||...|.|::..|..|:||||.: :::..|..:.:.......| :|..|.:
plant   459 LYLHEDSQLKIIHRDLKASNILLDAEMNPKVADFGTA-RLFDSDETRAETKRIAGTRGYMAPEYL 522

  Fly   630 LYNKFSLESDVWAYGICLWEVFS 652
            .:.:.|.:|||:::|:.|.|:.|
plant   523 NHGQISAKSDVYSFGVMLLEMIS 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308
		KR	217..299	CDD:214527	9/33 (27%)
		PTKc_Musk	435..713	CDD:133181	70/230 (30%)
		Pkinase_Tyr	441..707	CDD:285015	69/224 (31%)
CRK40	NP_192366.1	Stress-antifung	29..127	CDD:279926
		Stress-antifung	<189..249	CDD:279926	9/35 (26%)
		S_TKc	348..606	CDD:214567	67/217 (31%)
		STKc_IRAK	354..611	CDD:270968	67/211 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050