DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nrk and CRK36

DIOPT Version :9

Sequence 1:	NP_477255.1	Gene:	Nrk / 36445	FlyBaseID:	FBgn0020391	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_192358.1	Gene:	CRK36 / 825779	AraportID:	AT4G04490	Length:	658	Species:	Arabidopsis thaliana

Alignment Length:	662	Identity:	137/662 - (20%)
Similarity:	237/662 - (35%)	Gaps:	215/662 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 LCREAAEKMLCAYAFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSR-- 179
            |||:..|...|.    .|.....|.:... |....:|.|       |   :.:.:.|:....|
plant    75 LCRKHYEVQACR----RCVDRASRTLLTQ-CRGKTEAYH-------W---DSENDANVSCLVRYS 124

  Fly   180 -----GHFRLPNCSSLPHYNASMRRPNCSYIGLTELKES---------EVSYDCRNGNGRFYMGT 230
                 |..:|....::||   |...|:.:   ||.:.:.         ||:......:...|.|.
plant   125 NIHRFGKLKLEPIGNVPH---SSLDPSSN---LTRISQEFAARANRTVEVASTADESSVLKYYGV 183

  Fly   231 MNVSKSGIP-------------------CQRWDTQYPHKHFQPPLVFHQLLEGENYCRNAGGEEP 276
            .:...:..|                   |.|.:.:|..:|              |:.| .||...
plant   184 SSAEFTDTPEVNMLMQCTPDLSSSDCNHCLRENVRYNQEH--------------NWDR-VGGTVA 233

  Fly   277 HPWCYTVDESVRWQHCDIPMCPDYVDPNAVD----LNTP-----------IKMEKFFTPSMIFLL 326
            .|.||     .||.        ||....|.|    :..|           :|..:.|.|..:.::
plant   234 RPSCY-----FRWD--------DYRFAGAFDNLERVPAPPRSPQTRQDYRVKKGRMFQPWSVVVV 285

  Fly   327 ---AGIG---FVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTSRETL 385
               .||.   |||.|       |.|:..:.:.|::                      :|.:.::.
plant   286 VFPTGINLAVFVAFV-------LAYRRMRRRIYTE----------------------INKNSDSD 321

  Fly   386 GGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQG 450
            |                .||:..:...:...||                     :......||||
plant   322 G----------------QATLRFDLGMILIATN---------------------EFSLENKLGQG 349

  Fly   451 AFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALGR 515
            .||.|::    |::|..::  :|||.|. ..|.|.:::|:.|..||....|.|:|:|||.|..|.
plant   350 GFGSVYK----GILPSGQE--IAVKRLA-GGSGQGELEFKNEVLLLTRLQHRNLVKLLGFCNEGN 407

  Fly   516 PMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHL-LQMAANIAAGMLYL---SERKF 576
            ...|::|::....|..|:.           .:|:..|....: .::...:|.|:|||   |:.:.
plant   408 EEILVYEHVPNSSLDHFIF-----------DEDKRWLLTWDVRYRIIEGVARGLLYLHEDSQLRI 461

  Fly   577 VHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFI-PIRWMPLESILYNKFSLESDV 640
            :||||...|.|::..|..|:||||:: :::..|..:|:.:..: ...:|..|.:.:.:||.:|||
plant   462 IHRDLKASNILLDAEMNPKVADFGMA-RLFNMDETRGETSRVVGTYGYMAPEYVRHGQFSAKSDV 525

  Fly   641 WAYGICLWEVFS--------------FALQPYFGLTHEEVI-KYIKEGNVLGCPDNTPLSVYALM 690
            :::|:.|.|:.|              ||.:.:.....|.:| .|:.|.     |.|..:.:..:.
plant   526 YSFGVMLLEMISGEKNKNFETEGLPAFAWKRWIEGELESIIDPYLNEN-----PRNEIIKLIQIG 585

  Fly   691 RRCWNRKPSERP 702
            ..|.....::||
plant   586 LLCVQENAAKRP 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308	21/101 (21%)
		KR	217..299	CDD:214527	16/100 (16%)
		PTKc_Musk	435..713	CDD:133181	75/288 (26%)
		Pkinase_Tyr	441..707	CDD:285015	75/282 (27%)
CRK36	NP_192358.1	Stress-antifung	29..124	CDD:279926	13/63 (21%)
		Stress-antifung	162..242	CDD:279926	17/99 (17%)
		STYKc	341..606	CDD:214568	75/281 (27%)
		STKc_IRAK	346..606	CDD:270968	75/276 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050