| Sequence 1: | NP_477255.1 | Gene: | Nrk / 36445 | FlyBaseID: | FBgn0020391 | Length: | 724 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006171.2 | Gene: | NTRK2 / 4915 | HGNCID: | 8032 | Length: | 838 | Species: | Homo sapiens |
| Alignment Length: | 680 | Identity: | 202/680 - (29%) |
|---|---|---|---|
| Similarity: | 310/680 - (45%) | Gaps: | 139/680 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 130 AFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHFRLPNCSSLPHYN 194
Fly 195 ASMRRPNCSYIGLTELKESEVSYDCR-----------------------NGNGR-----FYMGTM 231
Fly 232 NVSKSGIPCQRWDTQYPHKHFQPPLVFHQLLEGENYCRNAGGEEPHPWCYTV--------DES-- 286
Fly 287 ----VRWQHCDIPMCPDYVD-----------------------PNAVDLNTPIKMEKFFTPSMIF 324
Fly 325 LLAGIGFVAIVTLHLMILLVYKLSKH-----KDYS----------QPAGAATAECSVSMRGGGDC 374
Fly 375 GGNLNTSRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAK-------GTKPNARLE 432
Fly 433 KLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLA 497
Fly 498 EFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAA 562
Fly 563 NIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIRWMPLE 627
Fly 628 SILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLSVYALMRR 692
Fly 693 CWNRKPSERPGFAEINHCIQHSIAESECKA 722 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nrk | NP_477255.1 | CRD_FZ | 67..212 | CDD:295308 | 16/81 (20%) |
| KR | 217..299 | CDD:214527 | 18/123 (15%) | ||
| PTKc_Musk | 435..713 | CDD:133181 | 134/277 (48%) | ||
| Pkinase_Tyr | 441..707 | CDD:285015 | 132/265 (50%) | ||
| NTRK2 | NP_006171.2 | LRR_8 | 92..150 | CDD:404697 | |
| LRR 1 | 92..113 | ||||
| LRR 2 | 116..137 | ||||
| TPKR_C2 | 152..195 | CDD:407151 | |||
| Ig | 205..283 | CDD:416386 | 15/85 (18%) | ||
| Ig strand A' | 205..209 | CDD:409353 | 1/3 (33%) | ||
| Ig strand B | 212..221 | CDD:409353 | 0/8 (0%) | ||
| Ig strand D | 238..243 | CDD:409353 | 2/4 (50%) | ||
| Ig strand E | 244..254 | CDD:409353 | 2/9 (22%) | ||
| Ig strand F | 261..270 | CDD:409353 | 1/8 (13%) | ||
| Ig strand G | 273..283 | CDD:409353 | 1/9 (11%) | ||
| IgI_TrkB_d5 | 286..379 | CDD:409441 | 16/106 (15%) | ||
| Ig strand B | 301..305 | CDD:409441 | 0/3 (0%) | ||
| Ig strand C | 314..318 | CDD:409441 | 0/3 (0%) | ||
| Ig strand E | 344..348 | CDD:409441 | 1/3 (33%) | ||
| Ig strand F | 358..363 | CDD:409441 | 2/10 (20%) | ||
| Ig strand G | 371..374 | CDD:409441 | 1/2 (50%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 491..514 | 5/29 (17%) | |||
| PTKc_TrkB | 548..835 | CDD:270675 | 137/290 (47%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1026 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||