Protein Alignment Nrk and Ddr

DIOPT Version :9

• Sequence 1: NP_477255.1
• Gene: Nrk / 36445
• FlyBaseID: FBgn0020391
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Alignment Length: 569
• Identity: 156/569 - (27%)
• Similarity: 237/569 - (41%)
• Gaps: 146/569 - (25%)

  Fly   216 SYDCRNGNGRF-YMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFHQLLEGENYCRNAGGEEPHPW 279
            |.|..||||.. .:.||:.::|.|              ....::|:......|...|..
  Fly   545 SPDTLNGNGVLKVVTTMDDNESSI--------------DKNSLYHEPFNANMYTSAASA------ 589

  Fly   280 CYTVDESVRWQHCDIPMCPDYVD-PNAVDLNTPIKMEKFFTPSMIFLLAGIGFVAIVTLHLMILL 343
            |...|  ::.||    :.|||.| |:.|       .:.:..|.|..||..
  Fly   590 CPMND--LQRQH----VSPDYTDVPDIV-------CQDYAVPHMQQLLPN--------------- 626

  Fly   344 VYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGN----LNTSRETLGGNGNTNT----------- 393
                      :.|.|:.   |......|...|.:    :.|.:.|.....:.|.
  Fly   627 ----------APPCGSG---CGTGTGTGPGRGSSPEFVVATGKVTASARNSLNAATLPLPSPPVP 678

  Fly   394 --LAKW----------------GTIRSTATIHSNCVALTTVT------------------NVSDA 422
              |.|:                |: :|:.::.|:..|.||.|                  |.:|.
  Fly   679 PPLEKYYAATPVSSKPMPVAPPGS-QSSGSLSSSTTAATTPTSGVVGVGKPHHYNLDMSANFADI 742

  Fly   423 KGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQM 487
            ...:.|.:::  |:||..:|.|..||.|.||.:.......|    ...||||..|:..|:|.::.
  Fly   743 NEERANCQVQ--EFPRQSLVIVEKLGSGVFGELHLCETNVL----NATLVAVATLRPGANDHLRK 801

  Fly   488 DFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYM-APGDLSEFLRACSPYATHQAPTQDRLQ 551
            :|..:|..||:...||:.||:|.|....|:|::.:|. ..|||::||:      .|.|.|...:.
  Fly   802 EFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFLQ------EHVAETSGLMA 860

  Fly   552 LNELH---LLQMAANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFG--LSHKIYLQDY- 610
            ...|.   |:.:|..||:||.:|.:..|||||||||:|:|...:.||:...|  ::...|..||
  Fly   861 KKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYC 925

  Fly   611 ----YKGDENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFAL-QPYFGLTHEEVIKYI 670
                :.|.::..:|||||..||:|..||:.:||||::.:.|||:.:||. |||..|:.:.||:.|
  Fly   926 QLEGFTGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENI 990

  Fly   671 -------KEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEINHCIQ 712
                   |...:|..|.|.|..:|.||..||.|..|.||.|.||:..:|
  Fly   991 GLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYLQ 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308
		KR	217..299	CDD:214527	16/82 (20%)
		PTKc_Musk	435..713	CDD:133181	109/297 (37%)
		Pkinase_Tyr	441..707	CDD:285015	103/284 (36%)
Ddr	NP_001014474.3	FA58C	106..262	CDD:214572
		FA58C	109..261	CDD:238014
		PTKc_DDR	753..1040	CDD:270644	109/297 (37%)
		TyrKc	759..1038	CDD:197581	105/288 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940