Protein Alignment Nrk and Ror2

DIOPT Version :9

• Sequence 1: NP_477255.1
• Gene: Nrk / 36445
• FlyBaseID: FBgn0020391
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_017455997.1
• Gene: Ror2 / 306782
• RGDID: 1305275
• Length: 950
• Species: Rattus norvegicus
• Alignment Length: 724
• Identity: 222/724 - (30%)
• Similarity: 338/724 - (46%)
• Gaps: 106/724 - (14%)

  Fly     9 VVERVLRGMVLK--WGANLAVLGL---------CVFLFASATHANSLNAIEEP------VTRRHH 56
            ||:...|.::.|  :|:.|.:..|         ||     ||  |.|..|...      :...|.
  Rat   109 VVQEPRRVIIRKTEYGSRLRIQDLDTTDTGYYQCV-----AT--NGLKTITATGVLYVRLGPTHS 166

  Fly    57 QRHH-EREREENGYCAPYSGKVCKEYLTGQVWYSLEDPTGGWKNEQVTTALWDELISDLTGL--- 117
            ..|: :.:.:|:|:|.||.|..|..::..:..|.......|....::|.|.  .:|...|.|
  Rat   167 PNHNFQDDDQEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAF--TMIGTSTHLSDQ 229

  Fly   118 CREAAEKMLCAYAFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHF 182
            |.:.|....|.:.||.|...........||.::|:......|..::.:...    |..|..|  .
  Rat   230 CSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLENDLCRQEYTIARS----NPLILMR--L 288

  Fly   183 RLPNCSSLPHYNASMRRPNCSYIGLTELKESEVSYDCRNGNGRFYMGTMNVSKSGIPCQRWDTQY 247
            :||.|.:|| ...|....||..||:...:.... :.|.||:|..|.|..:.:|||..||.|..|:
  Rat   289 QLPKCEALP-MPESPDAANCMRIGIPAERLGRY-HQCYNGSGTDYRGMASTTKSGHQCQPWALQH 351

  Fly   248 PHKHFQPPLVFHQLLEGENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNTPI 312
            ||.|......|.:|..|..||||.||:...|||:|.:::||.:.||:|.|            :|.
  Rat   352 PHSHRLSSTEFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRVELCDVPPC------------SPR 404

  Fly   313 KMEKFFTPSMIFLLAGIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGN 377
            ...|.   .::::|     |..:.:.|:|..::.|.......|.|.|:|.:
  Rat   405 DGSKM---GILYIL-----VPSIAIPLVIACLFFLVCMCRNKQKASASTPQ-------------- 447

  Fly   378 LNTSRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIV 442
                                  .|......|..:.:..::....||       |:::..  ..:.
  Rat   448 ----------------------RRQLMASPSQDMEMPLISQHKQAK-------LKEISL--STVR 481

  Fly   443 YVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRL 507
            ::..||:..||:|::....|..|.:...:||:|.|||.|...::.:|.:||.|.|...|||||.|
  Rat   482 FMEELGEDRFGKVYKGHLFGPAPGEPTQVVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCL 546

  Fly   508 LGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELH---LLQMAANIAAGML 569
            |||....:|:.::|.|...|||.|||...||::...:...||...:.|.   .:.:.|.|||||.
  Rat   547 LGVVTKDQPLSMVFSYCCHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHVVAQIAAGME 611

  Fly   570 YLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIRWMPLESILYNKF 634
            :||....||:||||||.|:.:.:.|:|:|.||..::|..||||...|..:|||||..|:::|.||
  Rat   612 FLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREVYSADYYKLMGNSLLPIRWMSPEAVMYGKF 676

  Fly   635 SLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPS 699
            |::||:|:||:.||||||:.||||.|.::::|::.|:...||.|||:.|..|||||..|||..||
  Rat   677 SIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPS 741

  Fly   700 ERPGFAEIN 708
            .||.|.:|:
  Rat   742 GRPRFKDIH 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308	36/147 (24%)
		KR	217..299	CDD:214527	35/81 (43%)
		PTKc_Musk	435..713	CDD:133181	118/277 (43%)
		Pkinase_Tyr	441..707	CDD:285015	117/268 (44%)
Ror2	XP_017455997.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7587
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222671at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920