Protein Alignment TppII and TPP2

DIOPT Version :9

• Sequence 1: NP_725252.1
• Gene: TppII / 36444
• FlyBaseID: FBgn0020370
• Length: 1441
• Species: Drosophila melanogaster
• Sequence 2: NP_193817.2
• Gene: TPP2 / 827833
• AraportID: AT4G20850
• Length: 1380
• Species: Arabidopsis thaliana
• Alignment Length: 1444
• Identity: 435/1444 - (30%)
• Similarity: 680/1444 - (47%)
• Gaps: 219/1444 - (15%)

  Fly    80 SDKSAESRMATSG--------------------IVESFPTGALVPKAETGVLNFLQKYPEYDGRD 124
            ||....||:...|                    :.||....:|:||.|.....|::.:||||||.
plant    74 SDTLTASRVGCGGGGGGGAVGGGAENASVANFKLNESTFIASLMPKKEIRADCFIEAHPEYDGRG 138

  Fly   125 VTIAIFDSGVDPRATGLETLCDGKTVKVIERYDCSGCGDVDMKKKVTPDENGNIKGLSGNSLKLS 189
            |.|||||||.||.|.||....|||. ||::..||:|.||:|....|..:|:|:|:|.||.:|.::
plant   139 VVIAIFDSGFDPSAAGLHVTSDGKP-KVLDVIDCTGSGDIDTSTVVKANEDGHIRGASGATLVVN 202

  Fly   190 PELMALNTDPEKAVRVGLK----SFSDLLPSKVRNNIVAQAKLKHWDKPHKTATANASRKIVEFE 250
            ...    .:|....|||.|    .|:|.|.|:|:     :.:.|.||:.::...|.|...:.:|:
plant   203 SSW----KNPTGEWRVGSKLVYQLFTDDLTSRVK-----KERRKSWDEKNQEEIAKAVNNLYDFD 258

  Fly   251 SQNPG-EASKLPWDKKILKENLDFELEMLNSYEKVYGDIKTSYDCILFPTADGWLTIVDTTEQGD 314
            .::.. |.:||...::.|:..:||..:..:.||    |.....|.:::...:.|...:||....:
plant   259 QKHSKVEDAKLKKTREDLQSKVDFLKKQADKYE----DKGPVIDAVVWHDGEVWRVALDTQSLEE 319

  Fly   315 LDQALRIGEYS--------RTHETRNVDDFLSISVNVHDEGNVLEVVGMSSPHGTHVSSIASGNH 371
            ...:.::.::|        |.:...:..|..|...||:|||.||.:|..||||||||:.||:.:|
plant   320 DPDSGKLADFSPLTNYRIERKYGVFSRLDACSFVANVYDEGKVLSIVTDSSPHGTHVAGIATAHH 384

  Fly   372 SSRD-VDGVAPNAKIVSMTIGDGRLGSMETGTALVRAMTKVMELCRDGRRIDVINMSYGEHANWS 435
            .... ::||||.|:|:|..|||.|||||||||.|.||:...:|     ...|::||||||.|...
plant   385 PEEHLLNGVAPGAQIISCKIGDSRLGSMETGTGLTRALIAALE-----HNCDLVNMSYGEPALLP 444

  Fly   436 NSGRIGELMNEVVNKYGVVWVASAGNHGPALCTVGTPPDISQPSLIGVGAYVSPQMMEAEYAMRE 500
            :.||..:|:.|.|||..:::|:||||.||||.|||.|...:. |:|||||||||.|....:::.|
plant   445 DYGRFVDLVTEAVNKRRLIFVSSAGNSGPALTTVGAPGGTTS-SIIGVGAYVSPAMAAGAHSVVE 508

  Fly   501 -KLPGNVYTWTSRDPCIDGGQGVTVCAPGGAIASVPQFTMSKSQLMNGTSMAAPHVAGAVALLIS 564
             ...|..|||:||.|..||..||.:.|||||:|.||.:|:.:..||||||||:|...||:|||:|
plant   509 PPSEGLEYTWSSRGPTSDGDLGVCISAPGGAVAPVPTWTLQRRMLMNGTSMASPSACGAIALLLS 573

  Fly   565 GLKQQNIEYSPYSIKRAISVTATKLGYV--DPFAQGHGLLNVEKAFEHLTEHRQSKDNMLRFSVR 627
            .:|.:.|..||||::||:..|:|.:|.:  |....|.||:.|:||:|:|.:.:.......:..|.
plant   574 AMKAEGIPVSPYSVRRALENTSTPVGDLPEDKLTTGQGLMQVDKAYEYLKQFQDYPCVFYQIKVN 638

  Fly   628 VGNN---ADKGIHLRQGVQ-RNSIDYNVYIEPIFY----NDKEADPKDKFNFNVRLNLIAS-QPW 683
            :...   ..:||:||:|.. |.|.::.:.::|.|:    |.||..|     |...|.|.:: :..
plant   639 LSGKTIPTSRGIYLREGTACRQSTEWTIQVDPKFHEGASNLKELVP-----FEECLELHSTDEGV 698

  Fly   684 VQCGAFLDLSYGTRSIAVRVDPTGLQPGVHSAVIRAYDTDCVQKGSLFEIPVTVVQPHVLESDQN 748
            |:...:|.|:...|...|.||||.|..|||...:...|....::|.||.||||::.|..:.:...
plant   699 VRVPDYLLLTNNGRGFNVVVDPTNLGDGVHYFEVYGIDCKAPERGPLFRIPVTIIIPKTVANQPP 763

  Fly   749 TPVFEPASSKGDNSVEFQPNTIQRDFILVPERATWAELRMRIT--DPNRGEDIGKFFVHTNQLLP 811
            ...|:..|        |....|:|.:|.||..|||||..||.:  |..|     :|::.|.|:.|
plant   764 VISFQQMS--------FISGHIERRYIEVPHGATWAEATMRTSGFDTTR-----RFYIDTLQVCP 815

  Fly   812 KQSCRKLETMKIVSVGSENESIMAFKVKSGRILELCIAKYWSNYGQSH----LKYSLRFRGVEAH 872
            .:  |.::.....:..|.:.....|.|.||:.:||.||::||:...|.    :.:.:.|.||..
plant   816 LR--RPIKWESAPTFASPSAKSFVFPVVSGQTMELAIAQFWSSGLGSREPTIVDFEIEFHGVGV- 877

  Fly   873 NPNAYVMHAGRGIHKLEIEALVA-EDVQPQLQLKNAEVVLKPTEAKISPLSATRDVIPDGRQVYQ 936
            :....::.......|:|.|||:| |.:.|...|....|..:|.:|::..||..||.:..|:|:..
plant   878 DKEELLLDGSEAPIKVEAEALLASEKLVPIAVLNKIRVPYQPIDAQLKTLSTGRDRLLSGKQILA 942

  Fly   937 NLLAFNLNVAKAADVSIYAPIFNDLLYEAEFESQMWMLFDANKALVATGDAHSHTSFTKLDKGEY 1001
            ..|.:...:..:|:|..|.|:.|:.:|:.:||||.:|:.|.||.:.|.||.:..:|  ||.||||
plant   943 LTLTYKFKLEDSAEVKPYIPLLNNRIYDTKFESQFFMISDTNKRVYAMGDVYPESS--KLPKGEY 1005

  Fly  1002 TIRLQVRHEKRDLLEKISEANLVASFKLTSPLTLDFYENYNQCIVGGRKYVSSPLRLSTR-VLYI 1065
            .::|.:|||..:||||:.:..:.....: ..:.|:.:...:....|...:.||.|....: ..|:
plant  1006 KLQLYLRHENVELLEKLKQLTVFIERNM-GEIRLNLHSEPDGPFTGNGAFKSSVLMPGVKEAFYL 1069

  Fly  1066 APITQERLTKANLPAQCAWLSGNLVFPQDEVGRRVAQHPFTYILNPAEKKSHTNGSSNGSSAAGS 1130
            .|.|:::|.| |.|      .|:::..:...|:          |:..||:
plant  1070 GPPTKDKLPK-NTP------QGSMLVGEISYGK----------LSFDEKE--------------- 1102

  Fly  1131 TATAAAVTTANGAKPKAPATPQAATSVTNPAAGDGISVQNDPPVDSSGSPASPKKGKANADDYAE 1195
                       |..||           .||.:         .|:.....|..|::.|
plant  1103 -----------GKNPK-----------DNPVS---------YPISYVVPPNKPEEDK-------- 1128

  Fly  1196 SFRDFQCSQIVKCELEMAEKIYNDVVAAHPKHLQANLLLIQNIESNQ---------LKSQLP--- 1248
                 :.:....|...::|::..:|.....|.| .||.  |..|..:         |||:.|
plant  1129 -----KAASAPTCSKSVSERLEQEVRDTKIKFL-GNLK--QETEEERSEWRKLCTCLKSEYPDYT 1185

  Fly  1249 --LTFVNAQKTSPPEAGESADKQKEDQKKVRSALERIVKLADKVIQETDSEALLSYYGLKNDTRA 1311
              |..:.....|..:||:.....:|           |::.|::|::..|.:.|..:...|.:...
plant  1186 PLLAKILEGLLSRSDAGDKISHHEE-----------IIEAANEVVRSVDVDELARFLLDKTEPED 1239

  Fly  1312 D-AAKIKTNMDKQKNTLIEALSKKGIAVAKLAVL----------DDCIKDSLAEINELYTEIIKF 1365
            | |.|:|..|:..::.|.:||.:||:|:|::..|          :...||   :..|.:.|:.|:
plant  1240 DEAEKLKKKMEVTRDQLADALYQKGLAMARIENLKGEKEGEGEEESSQKD---KFEENFKELTKW 1301

  Fly  1366 VDANDSKAIQFALWHAYAHGHYGRMYKYVVKLI--EEKRTRDHFVELAA-INGALGHEHIRTVIN 1427
            ||...||.....:.........|...|.:..||  |.:.......||.. :...:|..|:.|...
plant  1302 VDVKSSKYGTLTVLREKRLSRLGTALKVLDDLIQNENETANKKLYELKLDLLEEIGWSHLVTYEK 1366

  Fly  1428 RMMITAFPSSFRLF 1441
            :.|...||.|..||
plant  1367 QWMQVRFPKSLPLF 1380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TppII	NP_725252.1	Peptidases_S8_Tripeptidyl_Aminopeptidase_II	101..589	CDD:173796	203/502 (40%)
		Peptidase_S8	331..600	CDD:278510	132/272 (49%)
		TPPII	892..1073	CDD:289357	56/182 (31%)
		TPPII_N	1144..1257	CDD:289360	22/126 (17%)
TPP2	NP_193817.2	Peptidases_S8_Tripeptidyl_Aminopeptidase_II	116..598	CDD:173796	203/501 (41%)
		Peptidase_S8	364..604	CDD:278510	121/245 (49%)
		TPPII	897..1078	CDD:289357	56/183 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	316	1.000	Domainoid score	I294
eggNOG	1	0.900	-	-		E1_COG1404
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2471
Inparanoid	1	1.050	564	1.000	Inparanoid score	I247
OMA	1	1.010	-	-		QHG58290
OrthoDB	1	1.010	-	-		D156304at2759
OrthoFinder	1	1.000	-	-		FOG0005779
OrthoInspector	1	1.000	-	-		oto3355
orthoMCL	1	0.900	-	-		OOG6_104037
Panther	1	1.100	-	-	LDO	PTHR43806
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4170
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840