Protein Alignment TppII and AIR3

DIOPT Version :10

• Sequence 1: NP_725252.1
• Gene: TppII / 36444
• FlyBaseID: FBgn0020370
• Length: 1441
• Species: Drosophila melanogaster
• Sequence 2: NP_565309.2
• Gene: AIR3 / 814953
• AraportID: AT2G04160
• Length: 772
• Species: Arabidopsis thaliana
• Alignment Length: 944
• Identity: 186/944 - (19%)
• Similarity: 295/944 - (31%)
• Gaps: 339/944 - (35%)

  Fly    12 LRLYKNFGLLGQKASVGLTLPIISL----------SRPYMAYMGTERSVVMITAPA---TKE--- 60
            ::|..||..|       |.|.::.:          |..|:.|.|....|..||..|   .||
plant     1 MKLTHNFSFL-------LLLLLVHMSSKHILASKDSSSYVVYFGAHSHVGEITEDAMDRVKETHY 58

  Fly    61 -----FAESSERSNSSKKTTNKEQSDKSAESRMATSGIVESFP--TGALVPKAETGVLNFLQKYP 118
                 |..|.||                     ||..|..|:.  ........:..:...:.|:|
plant    59 DFLGSFTGSRER---------------------ATDAIFYSYTKHINGFAAHLDHDLAYEISKHP 102

  Fly   119 EYDGRDVTIAIFDSGVDPRATGLETLCDGKTVKVIERYDCSGCGDVDMKKKVTPDENGNIKGLSG 183
            |      .:::|.:    :|..|.|                             ..:.:..||..
plant   103 E------VVSVFPN----KALKLHT-----------------------------TRSWDFLGLEH 128

  Fly   184 NS----------LKLSPELMALNTD----PEKAVRVGLKSFSD----LLPSKVRNNIVAQAKLKH 230
            ||          .:...:.:..|.|    ||.      |||.|    .:||:
plant   129 NSYVPSSSIWRKARFGEDTIIANLDTGVWPES------KSFRDEGLGPIPSR------------- 174

  Fly   231 WD---KPHKTATANASRKIVEFESQNPGEASKLPWDKKILKENLDFELEMLNSYEKVYGDIKTSY 292
            |.   :..|.||.:.:||::.....|.|.|:.:...........|.:....::.....||.....
plant   175 WKGICQNQKDATFHCNRKLIGARYFNKGYAAAVGHLNSSFDSPRDLDGHGSHTLSTAAGDFVPGV 239

  Fly   293 DCILFPTADGWLTIVDTTEQGDLDQALRIGEYS------RTHETRNVDDFLSISVNVHDEGNVLE 351
            .  :|...:|       |.:|...:| |:..|.      :.:|..:.|...:....:||..:|:.
plant   240 S--IFGQGNG-------TAKGGSPRA-RVAAYKVCWPPVKGNECYDADVLAAFDAAIHDGADVIS 294

  Fly   352 V-------------VGMSSPHGTH---VSSIASGNHSSRD--VDGVAPNAKIV-----------S 387
            |             |.:.|.|...   |...::||....|  |..|||....|           :
plant   295 VSLGGEPTSFFNDSVAIGSFHAAKKRIVVVCSAGNSGPADSTVSNVAPWQITVGASTMDREFASN 359

  Fly   388 MTIGDGR--LGSMETGTALVRA-----MTKVMELCRDGRRIDVINMSYGEHANWSNSGRI----- 440
            :.:|:|:  .|...:.|||..|     |..|....::...:|......|........|:|
plant   360 LVLGNGKHYKGQSLSSTALPHAKFYPIMASVNAKAKNASALDAQLCKLGSLDPIKTKGKILVCLR 424

  Fly   441 GELMNEVVNKYGVVWVASAGNHGPAL------------------CTVGTPPD-------ISQ--- 477
            |:  |..|.|...  ||..|..|..|                  .|..|..|       |||
plant   425 GQ--NGRVEKGRA--VALGGGIGMVLENTYVTGNDLLADPHVLPATQLTSKDSFAVSRYISQTKK 485

  Fly   478 ------PSLIGVGAYVSPQMMEAEYAMREKLPGNVYTWTSRDPCIDGGQ---------GVTVCAP 527
                  ||...:|...:|.|.               :::|:.|.|...|         ||:|.|.
plant   486 PIAHITPSRTDLGLKPAPVMA---------------SFSSKGPSIVAPQILKPDITAPGVSVIAA 535

  Fly   528 -GGAIASVPQFTMSKSQLMN---GTSMAAPHVAGAVALLISGLKQQNIEYSPYSIKRAISVTATK 588
             .||::...:....:..|.|   ||||:.||::|...|    ||.:...:||.:|:.||..|||.
plant   536 YTGAVSPTNEQFDPRRLLFNAISGTSMSCPHISGIAGL----LKTRYPSWSPAAIRSAIMTTATI 596

  Fly   589 LGYV------------DPFAQGHGLLNVEKAFEHLTEHRQSKDNMLRFSVRVGNNADKGIHLRQG 641
            :..:            .||:.|.|             |.|.     ..:|..|...|.||.
plant   597 MDDIPGPIQNATNMKATPFSFGAG-------------HVQP-----NLAVNPGLVYDLGIK---- 639

  Fly   642 VQRNSIDYNVYIEPIFYNDKEADPKDKFNFNVRLNLIASQPWVQCGAFLDLSYGTRSIAVRVDPT 706
                  ||..::..:.||   |.....|:.|   |...|.|.:   :.::|:|          |:
plant   640 ------DYLNFLCSLGYN---ASQISVFSGN---NFTCSSPKI---SLVNLNY----------PS 679

  Fly   707 GLQPGVHSAVIRAYDT-DCVQKGSLFEIPV-------TVVQPHVLE----SDQNTPVFEPASSKG 759
            ...|.:.|:.:....| ..|.:.|::.:.|       ..|:|..|.    .:|.|.......|||
plant   680 ITVPNLTSSKVTVSRTVKNVGRPSMYTVKVNNPQGVYVAVKPTSLNFTKVGEQKTFKVILVKSKG 744

  Fly   760 DNSVEFQPNTIQRDFILVPERATWAELRMRITDP 793
            :         :.:.::.  ....|::.:.|:..|
plant   745 N---------VAKGYVF--GELVWSDKKHRVRSP 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TppII	NP_725252.1	Peptidases_S8_Tripeptidyl_Aminopeptidase_II	101..589	CDD:173796	121/602 (20%)
		TPPII	892..1077	CDD:463636
		TPPII_N	1144..1257	CDD:403697
AIR3	NP_565309.2	Inhibitor_I9	31..116	CDD:428674	22/115 (19%)
		Peptidases_S8_3	113..595	CDD:173795	114/562 (20%)
		PA_subtilisin_like	359..490	CDD:239035	28/134 (21%)
		fn3_6	674..770	CDD:465493	20/115 (17%)