DRSC/TRiP Functional Genomics Resources

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Protein Alignment TppII and RSPO4

DIOPT Version :10

Sequence 1:NP_725252.1 Gene:TppII / 36444 FlyBaseID:FBgn0020370 Length:1441 Species:Drosophila melanogaster
Sequence 2:XP_016883328.1 Gene:RSPO4 / 343637 HGNCID:16175 Length:266 Species:Homo sapiens


Alignment Length:129 Identity:28/129 - (21%)
Similarity:37/129 - (28%) Gaps:49/129 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   429 GEHANWSNSGRIGELMNEVVNKYGVVW--------VASAGNHGPALCTV---------------G 470
            |....||.....|:..       |..|        ...||:...|.|.|               |
Human   142 GPWGGWSPCTHNGKTC-------GSAWGLESRVREAGRAGHEEAATCQVLSESRKCPIQRPCPGG 199

  Fly   471 TPPD------ISQPSLIGVGAYVSPQMMEAEYAMREKLPGNVYTWTSRDPCIDGGQGVTVCAPG 528
            .|.|      ..:|:..|.....:||::    :||  ||       .|.|......||.:..||
Human   200 EPQDRHTRLRWERPTGTGRTQITAPQIV----SMR--LP-------ERPPLAILSCGVHITFPG 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TppIINP_725252.1 Peptidases_S8_Tripeptidyl_Aminopeptidase_II 101..589 CDD:173796 28/129 (22%)
TPPII 892..1077 CDD:463636
TPPII_N 1144..1257 CDD:403697
RSPO4XP_016883328.1 Furin-like_2 35..135 CDD:464939
Blue background indicates that the domain is not in the aligned region.

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