Protein Alignment TppII and mbtps1

DIOPT Version :10

• Sequence 1: NP_725252.1
• Gene: TppII / 36444
• FlyBaseID: FBgn0020370
• Length: 1441
• Species: Drosophila melanogaster
• Sequence 2: NP_954683.2
• Gene: mbtps1 / 326710
• ZFINID: ZDB-GENE-030131-4909
• Length: 1074
• Species: Danio rerio
• Alignment Length: 308
• Identity: 80/308 - (25%)
• Similarity: 134/308 - (43%)
• Gaps: 71/308 - (23%)

  Fly   339 ISVNVHDEG---------NVLEVVGMSSP--------HGTHVSSIASGNHSSRDVDGVAPNAKIV 386
            :.|.|.|.|         ||.|....::.        |||.|:.:.:   |.|:..|.||::::.
Zfish   227 VKVAVFDTGLSEKHPHFKNVKERTNWTNEKTLDDGLGHGTFVAGVIA---SMRECQGFAPDSELH 288

  Fly   387 SMTIGDGRLGSMETG--TALVRAMTKVMELCRDGRRIDVINMSYGEHANWSNSGRIGELMNEVVN 449
            ...:......|..:.  .|...|:.|         :|||:|:|.| ..::.:...:.::.....|
Zfish   289 IFRVFTNNQVSYTSWFLDAFNYAILK---------KIDVLNLSIG-GPDFMDHPFVDKVWELTAN 343

  Fly   450 KYGVVWVASAGNHGPALCTVGTPPDISQPSLIGVGAYVSPQMMEAEYAMREKLPGNVYTWTSRDP 514
            |  |:.|::.||.||...|:..|.|  |..:||||..              ....|:..::||
Zfish   344 K--VIMVSAIGNDGPLYGTLNNPAD--QMDVIGVGGI--------------DFEDNIARFSSR-- 388

  Fly   515 CIDGGQGVTVC-APGGAIASVPQFTMSKS-----------QLMNGTSMAAPHVAGAVALLISGLK 567
                  |:|.. .|||.....|......|           :.::|||:|:|.|||||.||.|.:.
Zfish   389 ------GMTTWELPGGYGRVKPDIVTYGSGVRGSGLKEGCRSLSGTSVASPVVAGAVTLLASTVL 447

  Fly   568 QQNIEYSPYSIKRAISVTATKLGYVDPFAQGHGLLNVEKAFEHLTEHR 615
            .:.: .:|.|:|:|:..:|.:|..|:.|.||||.|::.:|::.|..::
Zfish   448 NREL-VNPASMKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYK 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TppII	NP_725252.1	Peptidases_S8_Tripeptidyl_Aminopeptidase_II	101..589	CDD:173796	70/280 (25%)
		TPPII	892..1077	CDD:463636
		TPPII_N	1144..1257	CDD:403697
mbtps1	NP_954683.2	Peptidases_S8_SKI-1_like	218..470	CDD:173805	71/282 (25%)