Protein Alignment TppII and Rspo1

DIOPT Version :10

• Sequence 1: NP_725252.1
• Gene: TppII / 36444
• FlyBaseID: FBgn0020370
• Length: 1441
• Species: Drosophila melanogaster
• Sequence 2: NP_619624.2
• Gene: Rspo1 / 192199
• MGIID: 2183426
• Length: 265
• Species: Mus musculus
• Alignment Length: 176
• Identity: 32/176 - (18%)
• Similarity: 49/176 - (27%)
• Gaps: 79/176 - (44%)

  Fly   127 IAIFDSGVDPR------ATGLETLCDGKTVKVIERYDCSGCGDVDMKKKVTPDENGNIKGLSGNS 185
            ||:...|:..:      |.|.:....|          |..|.:|          ||        .
Mouse    17 IAVGSRGIKGKRQRRISAEGSQACAKG----------CELCSEV----------NG--------C 53

  Fly   186 LKLSPELMALNTDPEKAVRVGLKSFSDLLPS------KVRN---NIVAQAKLKHWDK-------- 233
            ||.||:|..|      ..|..::.....|||      ..||   |...:.|::|.:.
Mouse    54 LKCSPKLFIL------LERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCT 112

  Fly   234 -----------------PHKTATANASRKIVEFESQNPGEASKLPW 262
                             |..:..||::     .|..:|.:.....|
Mouse   113 KCQEGLYLHKGRCYPACPEGSTAANST-----MECGSPAQCEMSEW 153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TppII	NP_725252.1	Peptidases_S8_Tripeptidyl_Aminopeptidase_II	101..589	CDD:173796	32/176 (18%)
		TPPII	892..1077	CDD:463636
		TPPII_N	1144..1257	CDD:403697
Rspo1	NP_619624.2	FU 1	34..85		18/84 (21%)
		Furin-like_2	42..142	CDD:464939	24/138 (17%)
		FU 2	91..135		4/43 (9%)
		TSP1_spondin	148..203	CDD:480609	1/6 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..192
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..265