DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ack-like and STY17

DIOPT Version :9

Sequence 1:	NP_001260935.1	Gene:	Ack-like / 36442	FlyBaseID:	FBgn0263998	Length:	1495	Species:	Drosophila melanogaster
Sequence 2:	NP_195303.2	Gene:	STY17 / 829731	AraportID:	AT4G35780	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	472	Identity:	119/472 - (25%)
Similarity:	195/472 - (41%)	Gaps:	103/472 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YEFLTESELQQYYNAVKNELKITNAAQFKYAADEDLRFIGLSRPEIRRLRKFYEKHFPHSYLSKI 73
            :|.||    |.|.:..:::....||.........::.|..:.||::               ||::
plant   150 FEALT----QAYKDHAQDDDSAVNAQLPNSRPMHEITFSTIDRPKL---------------LSQL 195

  Fly    74 KRLLQAPGTMVKREEAPGGGSQVAL-----DGSSASACSSL--AAKNGASSPSKVPNNK------ 125
            ..:|...|..::...|.......:|     ||.|......|  |.|.........|.:|
plant   196 TSMLGELGLNIQEAHAFSTADGFSLDVFVVDGWSQEETEGLKDALKKEIRKFKDQPCSKQKSITF 260

  Fly   126 --------HIIPA----------------DSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCL 166
                    .::||                ..:.:.|::..|.:|.:.:|.:.:.    :||||.|
plant   261 FEHDKSTNELLPACVEIPTDGTDEWEIDMKQLKIEKKVACGSYGELFRGTYCSQ----EVAIKIL 321

  Fly   167 CRERMQSNPM-EFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECL-KDSGLRV 229
            ..||:.:..: ||.:|..||..:.|:|:|:..|....:.:|.:|||.....|:.:.| |..|:
plant   322 KPERVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIYDFLHKHKGV-- 384

  Fly   230 SFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSR------ALGVG 288
              ..|.:|.:.||.:..||.||.|..:|||||...|:|:...:.||::|||::|      .:...
plant   385 --FKIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESGVMTAE 447

  Fly   289 KDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAI 353
            ...|:            |.|||.|.:..:.:.:||:::.:.|||:.: |..|::.||.||....:
plant   448 TGTYR------------WMAPEVIEHKPYDHRADVFSYAIVLWELLT-GELPYSYLTPLQAAVGV 499

  Fly   354 DAPNYQRLEQPDCCPSEYY----TLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQLKAVVNCTEPK 414
                .|:..:|. .|.|.:    .|:.||||.|.|.||.|.||.:.|     .||...|...|..
plant   500 ----VQKGLRPK-IPKETHPKLTELLEKCWQQDPALRPNFAEIIEML-----NQLIREVGDDERH 554

  Fly   415 KDHLLYRQGDIISVLDR 431
            ||    :.|...|.|.:
plant   555 KD----KHGGYFSGLKK 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	10/55 (18%)
		STYKc	133..396	CDD:214568	83/274 (30%)
		PTKc_Ack_like	137..398	CDD:270636	84/272 (31%)
		SH3	400..454	CDD:214620	9/32 (28%)
		CRIB	486..525	CDD:238077
STY17	NP_195303.2	ACT_TyrKc	178..244	CDD:153200	15/80 (19%)
STY17	NP_195303.2	STKc_MAP3K-like	301..541	CDD:270901	82/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000