Protein Alignment Ack-like and tnk1

DIOPT Version :9

• Sequence 1: NP_001260935.1
• Gene: Ack-like / 36442
• FlyBaseID: FBgn0263998
• Length: 1495
• Species: Drosophila melanogaster
• Sequence 2: NP_001073486.2
• Gene: tnk1 / 565029
• ZFINID: ZDB-GENE-030131-7427
• Length: 733
• Species: Danio rerio
• Alignment Length: 648
• Identity: 193/648 - (29%)
• Similarity: 290/648 - (44%)
• Gaps: 136/648 - (20%)

  Fly     8 LYEFLTESELQQYYNAVKNELKITNAAQFKYAADEDLRFIGLSRPEIRRLRKFYEKHFPHSYLSK 72
            ||:.|.:.:|:::|..:::.|.:|......|..:.||..||:|:|..|||.:..:::
Zfish     9 LYQLLADVQLERFYLRMRDGLNVTRMEHLSYVKEADLEQIGISKPGQRRLWEAVKRY-------- 65

  Fly    73 IKRLLQAPGTMVK--REEAPGGGSQVALDGSSASACSSLAAKNGASSPSKVPNNKHIIPADSISV 135
             |..::|...|||  ...||.|..|....||......:|..               :|....:..
Zfish    66 -KTNMRARSWMVKATNGRAPEGNDQSNAAGSGQGPVRALTC---------------LIQDRELLF 114

  Fly   136 NKQLGTGEFGIVQQGVWSNGNERI-QVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYGV 199
            ..:||:|.||:|::..|.....|: .||:|.| |........:||:|...|.|::|.||:.||||
Zfish   115 GDRLGSGSFGVVRKAEWHTPTGRVLPVAVKTL-RSGQVDLVSDFLQEVTSMQSLDHPNIIHLYGV 178

  Fly   200 VLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAAR 264
            || |..|.:|||||.|.||.:.|:   ||.....:..|..|:.||..||.|||.:|.||||||||
Zfish   179 VL-THPLKMVTELAPLGSLYDTLR---LRHGEYPLSRLWLFSTQIAAGMEYLESRRFIHRDLAAR 239

  Fly   265 NILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVC 329
            |:|:.::::|||.||||.|.|. .:|:|  ....:.::|.||||||.:....|::|||||.|||.
Zfish   240 NVLLAAREQVKIGDFGLMRGLD-DRDHY--IMTAHRRIPFAWCAPESLRTGSFSHASDVWMFGVT 301

  Fly   330 LWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYD 394
            |||||:|..:||..|:|.|||..::... :|||:|..||.|.|.:|.|||..::.:||.|.::..
Zfish   302 LWEMFTYCEEPWLGLSGRQILYRVEREG-ERLERPPDCPQELYAVMRKCWACNSTERPTFAQLTT 365

  Fly   395 QLPDMKPEQLKAVVNCTEPKKDHLLYRQGDIISVLDRNTGTPFWKGV-LSTGKTGYFNPSNTVAF 458
            .:.:.:|.::::|.:..||::  |..:..|:::|:|.......|||. ..|...|:|.|:.|...
Zfish   366 MVSEAQPMEVRSVKDIAEPRR--LSLQANDLVTVIDHGLDMCEWKGQNQRTLSVGWFPPALTAPA 428

  Fly   459 LEG-LPSSTRDSFSRVSDHRISKRKLRTEMISKP-QNDFKHTGHVGID----------------- 504
            |.. :|:|                  ...:||.| :....||||...|
Zfish   429 LTAVVPAS------------------GPTLISSPVRGSLHHTGHGDTDPGRSWGTPERIDDNRRW 475

  Fly   505 ---------------------------------GATFGDIAFLGSSQNYNHVPKQIVTPYKPSED 536
                                             |..||..|...|.|..|.....::...:...|
Zfish   476 RVPLAKEKEGSNLKKMAGMSRSLESVLGGPQDKGRGFGVNAAQRSDQRRNMQNNNVIQDPRRFSD 540

  Fly   537 IEQTPLLLPPTPTSPD--SLQ-------------TASGYFPEGANSGGAMGTSMNPTFIPSAE 584
            ....|   ||.|..|:  |::             ..||:.|:         |...|.|.|..:
Zfish   541 AVVIP---PPRPPPPNIKSIKPQMMMMFLDRRAANPSGWSPQ---------TQAQPQFQPQQQ 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	17/56 (30%)
		STYKc	133..396	CDD:214568	115/263 (44%)
		PTKc_Ack_like	137..398	CDD:270636	115/261 (44%)
		SH3	400..454	CDD:214620	15/54 (28%)
		CRIB	486..525	CDD:238077	15/89 (17%)
tnk1	NP_001073486.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426644at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820