DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ack-like and yes1

DIOPT Version :9

Sequence 1:NP_001260935.1 Gene:Ack-like / 36442 FlyBaseID:FBgn0263998 Length:1495 Species:Drosophila melanogaster
Sequence 2:NP_001008186.1 Gene:yes1 / 493548 XenbaseID:XB-GENE-495082 Length:537 Species:Xenopus tropicalis


Alignment Length:411 Identity:130/411 - (31%)
Similarity:181/411 - (44%) Gaps:97/411 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 YYNAVKNELKITNAAQFKYAADEDLRFIGLSRPEIRRLRKFYEKHFPHSYLSKIKRLLQAPGTMV 84
            ||        ||..|||:               .:::|.|.|.:|                    
 Frog   216 YY--------ITTRAQFE---------------SLQKLVKHYSEH-------------------- 237

  Fly    85 KREEAPGGGSQVALDGSSASACSSLAAKNGASSPSKVPNNKHI------IPADSISVNKQLGTGE 143
                         .||    .|..|.    ...|:..|..:.:      ||.:|:.::.:||.|.
 Frog   238 -------------ADG----LCYRLT----TVCPTVKPQTQGLSKDAWEIPRESLRLDVKLGQGC 281

  Fly   144 FGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYGVVLATDSLML 208
            ||.|..|.| ||..:  ||||.|....|.  |..||:||.||..:.|:.:|.||.|| :.:.:.:
 Frog   282 FGEVWIGTW-NGTTK--VAIKTLKPGTMM--PEAFLQEAQIMKKLRHDKLVPLYAVV-SEEPIYI 340

  Fly   209 VTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDK 273
            |||.....|||:.||:...:  :|.:|.|.:.|.||.:||.|:|:...|||||.|.||||.....
 Frog   341 VTEYMTKGSLLDFLKEGDGK--YLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLV 403

  Fly   274 VKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGF 338
            .||:||||:|.: ...:|   ......|.||.|.|||...|.|||..||||:||:.|.|:.:.|.
 Frog   404 CKIADFGLARLI-EDNEY---TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 464

  Fly   339 QPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQ 403
            .|:..:...::||.::. .| |:..|..||...:.||..||:.|..:||.|..|...|.|     
 Frog   465 VPYPGMVNREVLEQVER-GY-RMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLED----- 522

  Fly   404 LKAVVNCTEPKKDHLLYRQGD 424
               ....|||:     |:.||
 Frog   523 ---YFTATEPQ-----YQPGD 535

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ack-likeNP_001260935.1 SAM_TNK-like 4..65 CDD:188938 10/44 (23%)
STYKc 133..396 CDD:214568 102/262 (39%)
PTKc_Ack_like 137..398 CDD:270636 103/260 (40%)
SH3 400..454 CDD:214620 6/25 (24%)
CRIB 486..525 CDD:238077
yes1NP_001008186.1 SH3_Yes 88..145 CDD:212940
SH2_Src_family 148..247 CDD:199827 15/94 (16%)
PTKc_Yes 258..536 CDD:270654 113/305 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D539311at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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