Protein Alignment Ack-like and zap70

DIOPT Version :9

• Sequence 1: NP_001260935.1
• Gene: Ack-like / 36442
• FlyBaseID: FBgn0263998
• Length: 1495
• Species: Drosophila melanogaster
• Sequence 2: NP_001006825.1
• Gene: zap70 / 448557
• XenbaseID: XB-GENE-956409
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 366
• Identity: 123/366 - (33%)
• Similarity: 192/366 - (52%)
• Gaps: 53/366 - (14%)

  Fly    50 SRPEIRRLRKFYEKHFPHSYLSKIKRLLQAPGTMVKREEAPGGGSQVALDGSSASACSSLAAKNG 114
            |.|:||:.....:.:.|..::.| .|:|....::.   |:|
 Frog   270 SLPKIRQAASNSDGYTPEPFIGK-SRILPMDTSVY---ESP------------------------ 306

  Fly   115 ASSPSKVPNNKHIIPADSISVNK-QLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEF 178
            .|.|.::...|..:..:.:.::: :||:|.||.|::||:.....:|.||||.|..:..::...|.
 Frog   307 YSDPEELKERKLFVKRELLLIDEVELGSGNFGCVKKGVYKLKKRQIDVAIKVLKVQDEKNVRDEM 371

  Fly   179 LKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAH---LRSLLECLKDSGLRVSFLTIPTLCEF 240
            :|||.|||.:::..|||:.||..| ::||||.|:|.   |...|...||      .:.:..:.|.
 Frog   372 MKEAEIMHQLDNPYIVRMIGVCEA-ENLMLVMEMASGGPLNKFLGAKKD------VIPMSNIVEL 429

  Fly   241 ALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKT-NFNVNLKLPI 304
            ..|:..||:|||.|..:||||||||:|:.::...||||||||:||.....|||. :|.   |.|:
 Frog   430 MHQVSIGMKYLEGKNFVHRDLAARNVLMVNQHYAKISDFGLSKALAADDSYYKAKSFG---KWPL 491

  Fly   305 AWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPS 369
            .|.|||||||.:|::.||||::|:.:||.|:||.:|:..|.|.:::..|:  ..:||..|..||.
 Frog   492 KWYAPECINYRKFSSRSDVWSYGITMWEAFTYGQKPYKKLKGTEVMSFIE--RNERLACPAGCPP 554

  Fly   370 EYYTLMMKCWQDDAAKRPRFGEI-------YDQLPDMKPEQ 403
            |.|.:|:.||......||.|..:       |..:.| ||::
 Frog   555 EMYQVMLDCWIFKMEDRPNFDNVEYRMRMYYYSIAD-KPDK 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	4/14 (29%)
		STYKc	133..396	CDD:214568	107/274 (39%)
		PTKc_Ack_like	137..398	CDD:270636	107/272 (39%)
		SH3	400..454	CDD:214620	2/4 (50%)
		CRIB	486..525	CDD:238077
zap70	NP_001006825.1	SH2_N-SH2_Zap70_Syk_like	8..111	CDD:198191
		SH2_C-SH2_Zap70	152..256	CDD:198265
		PKc_like	321..589	CDD:389743	107/279 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910