DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ack-like and uqcrfs1

DIOPT Version :9

Sequence 1:	NP_001260935.1	Gene:	Ack-like / 36442	FlyBaseID:	FBgn0263998	Length:	1495	Species:	Drosophila melanogaster
Sequence 2:	NP_988911.1	Gene:	uqcrfs1 / 394506	XenbaseID:	XB-GENE-5746219	Length:	273	Species:	Xenopus tropicalis

Alignment Length:	183	Identity:	45/183 - (24%)
Similarity:	75/183 - (40%)	Gaps:	40/183 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 SLAAKNGASSPSKVPNNKHIIPADSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIK--CLCRER 170
            |||.::|:.:|        .:.|.|.:|..||.....|:|.|.      :::.:.:|  .||||.
Frog     3 SLATRSGSVAP--------YLSATSYAVAGQLKPLVSGVVLQA------DKVLLDVKKPFLCRES 53

  Fly   171 MQSN-PMEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLR--SLLECLK----DSGLR 228
            :... |...|..:|   .|.....||.    |.:|  :.|.:.:..|  .:|:..|    .|..|
Frog    54 LNGQAPNGGLSASA---GINGAACVRF----LHSD--VTVPDFSDYRRPEVLDSTKSSQTSSDSR 109

  Fly   229 VSF---LTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISD 278
            .||   :|..|....|....|.:     .:.:....|:.::|..||.::|:||
Frog   110 KSFSYLVTGVTAVATAYAAKNAV-----TQFVTSMSASADVLAMSKIEIKLSD 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938
		STYKc	133..396	CDD:214568	38/158 (24%)
		PTKc_Ack_like	137..398	CDD:270636	37/154 (24%)
		SH3	400..454	CDD:214620
		CRIB	486..525	CDD:238077
uqcrfs1	NP_988911.1	Ubiq-Cytc-red_N	2..76	CDD:370333	22/89 (25%)
		UCR_TM	79..144	CDD:367251	14/71 (20%)
		Rieske_cytochrome_bc1	150..273	CDD:239552	4/8 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910