| Sequence 1: | NP_001260935.1 | Gene: | Ack-like / 36442 | FlyBaseID: | FBgn0263998 | Length: | 1495 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004094.3 | Gene: | PTK2B / 2185 | HGNCID: | 9612 | Length: | 1009 | Species: | Homo sapiens |
| Alignment Length: | 706 | Identity: | 179/706 - (25%) |
|---|---|---|---|
| Similarity: | 268/706 - (37%) | Gaps: | 241/706 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 128 IPADSISVNKQLGTGEFGIVQQGVWSN-GNERIQVAIKCLCRERMQSNPMEFLKEAAIMHSIEHE 191
Fly 192 NIVRLYGVVLATDSLMLVTEL---AHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQ 253
Fly 254 KRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFT 318
Fly 319 NASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDA 383
Fly 384 AKRPRFGEIYDQLPDMKPEQLKAVVNCTEPKKDHLLYR-QGDIISVLDRNTGTPFWKGVLSTGKT 447
Fly 448 GYFNPS--NTVAFLEGLPSSTRDSFSRVSDHRISKRKLRTEMISKPQNDFKHTGHVGIDGATFGD 510
Fly 511 IAFLGSSQNYNHVPKQIVTPYKPSEDIEQTPLLLP--------------PTPTSPDSLQTASGYF 561
Fly 562 PEGANSGGAMGTSMNPTFIPSAEHTPKLIATNGQSSFDFASGSTNPFFPNRGDDELEFGLHNYGA 626
Fly 627 DGKSVHSETGWRPTSRSIVDDPHEYHEISDDEIAADKLDFGPSLLDEINSMFGSISAATGSHPKS 691
Fly 692 PGFDHVNNKNEIT--------------EMSAKLGQKSGDTNGNKHGHGLLPTLSKKKSSGTVKPI 742
Fly 743 SVKDEKILNHAIEIANE-----------------ISARSMIDLVSDQTPVIHSPKR 781 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ack-like | NP_001260935.1 | SAM_TNK-like | 4..65 | CDD:188938 | |
| STYKc | 133..396 | CDD:214568 | 110/266 (41%) | ||
| PTKc_Ack_like | 137..398 | CDD:270636 | 110/264 (42%) | ||
| SH3 | 400..454 | CDD:214620 | 7/56 (13%) | ||
| CRIB | 486..525 | CDD:238077 | 0/38 (0%) | ||
| PTK2B | NP_004094.3 | B41 | 41..254 | CDD:214604 | |
| FERM_B-lobe | 150..254 | CDD:271216 | |||
| FERM_C_FAK1 | 261..368 | CDD:270011 | |||
| PTKc_FAK | 418..687 | CDD:133187 | 114/299 (38%) | ||
| TyrKc | 425..679 | CDD:197581 | 110/266 (41%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 701..725 | 9/84 (11%) | |||
| Interaction with TGFB1I1. /evidence=ECO:0000250 | 801..1009 | 23/150 (15%) | |||
| Focal adhesion targeting (FAT) | 868..1009 | 14/72 (19%) | |||
| Focal_AT | 872..1001 | CDD:281606 | 12/68 (18%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||