DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ack-like and EPHA8

DIOPT Version :9

Sequence 1:NP_001260935.1 Gene:Ack-like / 36442 FlyBaseID:FBgn0263998 Length:1495 Species:Drosophila melanogaster
Sequence 2:NP_065387.1 Gene:EPHA8 / 2046 HGNCID:3391 Length:1005 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ack-likeNP_001260935.1 SAM_TNK-like 4..65 CDD:188938
STYKc 133..396 CDD:214568
PTKc_Ack_like 137..398 CDD:270636
SH3 400..454 CDD:214620
CRIB 486..525 CDD:238077
EPHA8NP_065387.1 EphR_LBD 31..203 CDD:295439
fn3 330..423 CDD:278470
FN3 440..531 CDD:238020
Mediates interaction with ANKS1A and ANKS1B. /evidence=ECO:0000250 564..570
EphA2_TM <566..630 CDD:291255
Mediates interaction with PIK3CG and required for endocytosis. /evidence=ECO:0000250 589..644
PTKc_EphR_A 630..896 CDD:270651
Pkinase_Tyr 635..892 CDD:285015
SAM_EPH-A8 933..995 CDD:188949
SAM 934..994 CDD:197735
PDZ-binding. /evidence=ECO:0000255 1003..1005
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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