DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ack-like and EGFR

DIOPT Version :9

Sequence 1:NP_001260935.1 Gene:Ack-like / 36442 FlyBaseID:FBgn0263998 Length:1495 Species:Drosophila melanogaster
Sequence 2:NP_005219.2 Gene:EGFR / 1956 HGNCID:3236 Length:1210 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ack-likeNP_001260935.1 SAM_TNK-like 4..65 CDD:188938
STYKc 133..396 CDD:214568
PTKc_Ack_like 137..398 CDD:270636
SH3 400..454 CDD:214620
CRIB 486..525 CDD:238077
EGFRNP_005219.2 Recep_L_domain 57..168 CDD:279382
Approximate 75..300
Furin-like 185..335 CDD:279142
FU 231..274 CDD:238021
Recep_L_domain 361..481 CDD:279382
Approximate 390..600
GF_recep_IV 505..637 CDD:291509
FU 506..559 CDD:238021
FU 552..598 CDD:214589
TM_ErbB1 634..677 CDD:213054
Important for dimerization, phosphorylation and activation 688..704
PTKc_EGFR 704..1016 CDD:270683
TyrKc 713..968 CDD:197581
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1097..1137
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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