Protein Alignment Ack-like and Y69E1A.3

DIOPT Version :9

• Sequence 1: NP_001260935.1
• Gene: Ack-like / 36442
• FlyBaseID: FBgn0263998
• Length: 1495
• Species: Drosophila melanogaster
• Sequence 2: NP_502040.2
• Gene: Y69E1A.3 / 190549
• WormBaseID: WBGene00013475
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 526
• Identity: 136/526 - (25%)
• Similarity: 207/526 - (39%)
• Gaps: 150/526 - (28%)

  Fly    58 RKFYEKH--FPHSYLSKIKRLLQAPGTMVKREEAPGGGSQVALDGSSASACSSLAAKNGASSPSK 120
            :|.|||.  .|:.....|::||:|             .||                    ::|..
 Worm   136 KKLYEKFPTMPNRRFLHIRQLLEA-------------WSQ--------------------ATPFL 167

  Fly   121 V--PNNKHIIPADSISVNKQLGTGEFGIVQQGVW---SNGNERIQVAIKCLCRERMQSNPMEFLK 180
            :  |...:::...:|:::|:||.|.||.|.:|.:   .:.|..|:||:|.:.....:....||..
 Worm   168 IPTPRGSNVLIHSTINLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCN 232

  Fly   181 EAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLT---IPTL--CEF 240
            ||.||..::|||||..||.....:.:|:|.||         :....||..|.|   ||.|  ..|
 Worm   233 EAQIMTVLQHENIVAFYGFASLEEPIMVVMEL---------VTGGDLRKYFQTTQNIPKLQILWF 288

  Fly   241 ALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIA 305
            |:.:.:|||:|..|.:|||||||||.||....|.||||||||....|      |..|:. |.||.
 Worm   289 AMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTV------TTKNLE-KAPIR 346

  Fly   306 WCAPECINYLRFTNASDVWAFGVCLWEMFSY----GFQPWAALTGLQILEAIDAPNYQRLEQPDC 366
            |.|||.:....|...:|||::||.|.|:.:.    ...|.:.......:...:.|:  :::..|
 Worm   347 WLAPESLKSGLFNEKTDVWSYGVFLTELMTRCEHDPLYPKSLKDAKAWILTEERPH--KMKNGD- 408

  Fly   367 CPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDM-------------KPEQLKAVVNCTEPKKDHL 418
             |.|...|:..|.:.:..:|..|..:..|:.|:             |||.....|..::|.:|..
 Worm   409 -PKELMVLIDACCERNPNERLNFNTVKRQITDIYMEALNKGPQDGRKPENSAMTVLTSKPSEDRT 472

  Fly   419 ---LYRQGDIISVLDRNTGTPFWKGVLSTGKTGYFNPSNTVAFLEGLPSSTRDSFSRVSDHRISK 480
               |.|:..:    ||                            :.:|||::.||..      |.
 Worm   473 RISLNRKKSV----DR----------------------------QKIPSSSKRSFFS------SL 499

  Fly   481 RKLRTEMISKPQNDFKHTGHVGIDGATFGDIAFLGSSQNYNHVPKQIVTPYKPSEDIEQTPLLLP 545
            ||...:.::.|                    |.:..|.:.|       :...||.:...|....|
 Worm   500 RKKNKDQVTLP--------------------AGMSISPSTN-------SAKPPSSETPNTGSSSP 537

  Fly   546 PTPTSP 551
            ..||.|
 Worm   538 NAPTPP 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	4/8 (50%)
		STYKc	133..396	CDD:214568	92/274 (34%)
		PTKc_Ack_like	137..398	CDD:270636	92/272 (34%)
		SH3	400..454	CDD:214620	10/56 (18%)
		CRIB	486..525	CDD:238077	4/38 (11%)
Y69E1A.3	NP_502040.2	SH2	79..162	CDD:214585	9/38 (24%)
		STYKc	182..437	CDD:214568	92/274 (34%)
		PTKc	186..438	CDD:270623	92/271 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910