Protein Alignment Ack-like and T25B9.5

DIOPT Version :9

• Sequence 1: NP_001260935.1
• Gene: Ack-like / 36442
• FlyBaseID: FBgn0263998
• Length: 1495
• Species: Drosophila melanogaster
• Sequence 2: NP_001293881.1
• Gene: T25B9.5 / 188883
• WormBaseID: WBGene00012011
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 133/512 - (25%)
• Similarity: 208/512 - (40%)
• Gaps: 121/512 - (23%)

  Fly    58 RKFYEKH--FPHSYLSKIKRLLQA-PGTMVKREEAPGGGSQVALDGSSASACSSLAAKNGASSPS 119
            :|.|||.  .|:.....|::||:| |                                  .::|.
 Worm   134 KKLYEKFPTMPNRRFLHIRQLLEAWP----------------------------------QATPF 164

  Fly   120 KV--PNNKHIIPADSISVNKQLGTGEFGIVQQGVW---SNGNERIQVAIKCLCRERMQSNPMEFL 179
            .:  |...:::...:|:::|:||.|.||.|.:|.:   .:.|..|:||:|.:.....:....||.
 Worm   165 LIPTPRGSNVLIHSTINLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFC 229

  Fly   180 KEAAIMHSIEHENIVRLYGVVLATDSLMLVTEL---AHLRSLLECLKDSGLRVSFLTIPTL--CE 239
            .||.||..::|||||..||.....:.:|:|.||   ..||..|:..::         ||.|  ..
 Worm   230 NEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYLQTTQN---------IPKLQILW 285

  Fly   240 FALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPI 304
            ||:.:.:|||:|..|.:|||||||||.||....|.||||||||..   |.:....|..   |.||
 Worm   286 FAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQ---GTEVTTKNLE---KAPI 344

  Fly   305 AWCAPECINYLRFTNASDVWAFGVCLWEMFSY----GFQPWAALTGLQILEAIDAPNYQRLEQPD 365
            .|.|||.:....|...:|||::||.|.|:.:.    ...|.:.......:...:.|:  ::|..|
 Worm   345 RWLAPESLKSGMFNEKTDVWSYGVFLTELMARCEHDPLYPKSLKDAKAWILTEERPH--KMENGD 407

  Fly   366 CCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQL-KAVVNCTEPKKDHLLYRQGDIISVL 429
              |.|...|:..|.:.:..:|..|..:..|:.|:..|.| |...:..:|        :...::||
 Worm   408 --PKELMVLIDACCERNPNERLNFNTVKRQITDIYMEALNKGPQDGRKP--------ENSAMTVL 462

  Fly   430 DRNTGTPFWKGVLSTGKTGYFNPSNTVAFLEGLPSSTRDSFSRVSDHRISKRKLRTEMISKPQND 494
            ...|.....:..|:..|:         ...:.:|||::.||..      |.||...:.::.|
 Worm   463 TSKTSEDRTRISLNRKKS---------VDRQKIPSSSKRSFFS------SLRKKNKDQVTLP--- 509

  Fly   495 FKHTGHVGIDGATFGDIAFLGSSQNYNHVPKQIVTPYKPSEDIEQTPLLLPPTPTSP 551
                             |.:..|.:.|       :...||.:...|....|..||.|
 Worm   510 -----------------AGMSISPSTN-------SAKPPSSETPNTGSSSPNAPTPP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	4/8 (50%)
		STYKc	133..396	CDD:214568	91/274 (33%)
		PTKc_Ack_like	137..398	CDD:270636	91/272 (33%)
		SH3	400..454	CDD:214620	9/54 (17%)
		CRIB	486..525	CDD:238077	4/38 (11%)
T25B9.5	NP_001293881.1	SH2	77..158	CDD:214585	8/23 (35%)
		STYKc	180..436	CDD:214568	91/274 (33%)
		PTKc	184..437	CDD:270623	91/271 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910