DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ack-like and R151.1

DIOPT Version :9

Sequence 1:	NP_001260935.1	Gene:	Ack-like / 36442	FlyBaseID:	FBgn0263998	Length:	1495	Species:	Drosophila melanogaster
Sequence 2:	NP_001299880.1	Gene:	R151.1 / 187907	WormBaseID:	WBGene00020106	Length:	696	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	123/382 - (32%)
Similarity:	172/382 - (45%)	Gaps:	73/382 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 IRRLRKFYEK--HFPHSYLSKIKRLLQAPGTMVKREEAPGGGSQVALDGSSASACS--SLAAKNG 114
            :||.:|..:|  ||.|      :|.|                           :||  |:...|.
Worm   363 LRRRKKEIKKRHHFLH------RRSL---------------------------SCSRHSIIETNI 394

  Fly   115 ASSPSKVPN----NKHIIPADSISVNKQLGTGEFGIVQQGVWSNGN-ERIQVAIKCLCRERMQSN 174
            ...|....|    .:.:|....|.|...:|.|.||.|.:|:....| :.|.||:|.|....:...
Worm   395 LYRPPNEVNGGTTGEWLIRGQDIVVGAVIGEGAFGQVFKGILRGPNGQVIPVAVKQLKANAIDEE 459

  Fly   175 PMEFLKEAAIMHSI-EHENIVRLYGVVLATDSLMLVTE------LAHLRSLLECLKDSGLRV--- 229
            ..||::|..:|.:: :|:|||.:||..:......::.|      |.|....:...|||...:
Worm   460 REEFVREIQMMQTVGQHDNIVTMYGYCMDEQLQCMIMEYVPYGDLKHYLQNMRKEKDSDSAIDSK 524

  Fly   230 SFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKT 294
            .||:      |..||..||.:||...:||||||||||||.:...:||||||:||. ||   |.|.
Worm   525 EFLS------FTNQIACGMAHLESVGIIHRDLAARNILVGTGKVLKISDFGMSRP-GV---YIKM 579

  Fly   295 NFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQ 359
            :..|   :|:.|.:||.|....::|.||||||||.|||:.:.|..|:..:....||..:  ....
Worm   580 SKGV---IPLRWLSPEAIKDNTYSNKSDVWAFGVLLWEIATLGGFPYNNVADKDILNQL--TEGM 639

  Fly   360 RLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQLKAVVNCTEPKKD 416
            |||||..|..:.|.||..||...|..||.|..|..::     ||: |.|:...|..|
Worm   640 RLEQPAKCSDDMYILMKSCWNLKAEDRPSFLAILSKI-----EQI-ANVDADAPPSD 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	4/12 (33%)
		STYKc	133..396	CDD:214568	101/273 (37%)
		PTKc_Ack_like	137..398	CDD:270636	99/271 (37%)
		SH3	400..454	CDD:214620	6/17 (35%)
		CRIB	486..525	CDD:238077
R151.1	NP_001299880.1	PTKc	422..677	CDD:270623	99/274 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910