DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ack-like and LOC101733045

DIOPT Version :9

Sequence 1:	NP_001260935.1	Gene:	Ack-like / 36442	FlyBaseID:	FBgn0263998	Length:	1495	Species:	Drosophila melanogaster
Sequence 2:	XP_031757813.1	Gene:	LOC101733045 / 101733045	-ID:	-	Length:	568	Species:	Xenopus tropicalis

Alignment Length:	391	Identity:	120/391 - (30%)
Similarity:	172/391 - (43%)	Gaps:	51/391 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 EDLRFIGLSRPEIRRL--------RKFYEKHFPHSYLSKIK--------RLLQAPGTMVKREEAP 90
            ||..|.|:.|.:.:|.        ..|...|...||...::        |:.||.|.....|.|.
Frog   187 EDWYFGGIRRMDAKRFLLQEPNGSGSFLVWHSDASYWLSVRVEQTVRHYRITQAQGAYYLVERAA 251

  Fly    91 G---GGSQVALDGSSASACSSLAAKNGASSPSKVPNNKHI------IPADSISVNKQLGTGEFGI 146
            .   |...:.....|...|:.|..........::|:..|.      |..:||...::||.|.||:
Frog   252 FRTLGALVLYYQQQSDGLCTRLGKPCVWLDVPRMPSLCHTAVDQLEISPNSIERIRKLGRGSFGL 316

  Fly   147 VQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTE 211
            |..|.|   |...|||||.| :...||.......||..|..:.||.:::||.|.|....:.:|||
Frog   317 VWLGKW---NGTTQVAIKEL-QVTAQSLQKSLYGEADTMWKLSHERLLKLYAVCLQVSPVFIVTE 377

  Fly   212 LAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKI 276
            .....:|...|:|.....: |.:..|.:||.|||.||.|:||...:||||.|.|||:.:....||
Frog   378 YMERGTLKRYLRDHQQNRN-LELQQLMDFAAQICQGMGYMEQNLCVHRDLRAENILLSAMLSCKI 441

  Fly   277 SDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQPW 341
            .||||:|.:    |......:.:.::||.|.|||..:..|:::.||||:|||.|.|:.:||..|:
Frog   442 GDFGLARFM----DSSSIAMSADARIPIKWMAPEVFSEQRYSSKSDVWSFGVLLVEIVTYGKMPF 502

  Fly   342 AALTGLQILEAIDAPNYQR--------LEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPD 398
            ..:|..|         |.|        |:.|...|.....:|..||:..|..||.|.|:...:.|
Frog   503 PEITNEQ---------YVREMLREGGTLQPPRDAPDNVSYIMNMCWRRAAPTRPTFAELERLIMD 558

  Fly   399 M 399
            :
Frog   559 L 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938	7/30 (23%)
		STYKc	133..396	CDD:214568	95/270 (35%)
		PTKc_Ack_like	137..398	CDD:270636	94/268 (35%)
		SH3	400..454	CDD:214620	120/391 (31%)
		CRIB	486..525	CDD:238077
LOC101733045	XP_031757813.1	SH2	185..276	CDD:417686	20/88 (23%)
LOC101733045	XP_031757813.1	STYKc	303..556	CDD:214568	95/270 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010