DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ack-like and LOC100491469

DIOPT Version :9

Sequence 1:	NP_001260935.1	Gene:	Ack-like / 36442	FlyBaseID:	FBgn0263998	Length:	1495	Species:	Drosophila melanogaster
Sequence 2:	XP_031750439.1	Gene:	LOC100491469 / 100491469	-ID:	-	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	76/213 - (35%)
Similarity:	124/213 - (58%)	Gaps:	11/213 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 PADSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENI 193
            |.....:.:|||.|.||.|.:|:|:|   :.:||||...::.:  |..:|.||...:.::.|:|:
Frog   219 PRSEFKLVRQLGAGNFGEVWEGLWNN---KDKVAIKTFKQDNI--NESDFKKEVNALKTLCHKNL 278

  Fly   194 VRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIH 258
            ::||.|....:.:.:||||....|||:.|:  |.....||..:......|:..||.:||::.::|
Frog   279 IQLYAVCSVGEPVYIVTELMSKGSLLQFLR--GTEGRHLTAGSFMHIISQVAEGMVFLEKEHVVH 341

  Fly   259 RDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDV 323
            |||||||:||..|...|::||||:|.|  ..|.|  :...|:|:||.|.|||.:....::..|||
Frog   342 RDLAARNVLVGEKLVCKVADFGLARIL--KDDLY--SLQGNIKIPIKWTAPEVLTRSIYSTKSDV 402

  Fly   324 WAFGVCLWEMFSYGFQPW 341
            |::|:.::|::..|..|:
Frog   403 WSYGIVMYEVYMLGQMPY 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ack-like	NP_001260935.1	SAM_TNK-like	4..65	CDD:188938
		STYKc	133..396	CDD:214568	75/209 (36%)
		PTKc_Ack_like	137..398	CDD:270636	75/205 (37%)
		SH3	400..454	CDD:214620
		CRIB	486..525	CDD:238077
LOC100491469	XP_031750439.1	SH3_Srms	46..100	CDD:212780
		SH2	113..191	CDD:417686
		PKc_like	216..>422	CDD:419665	76/213 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010