Protein Alignment Cap-G and ncapg

DIOPT Version :10

• Sequence 1: NP_995827.2
• Gene: Cap-G / 36440
• FlyBaseID: FBgn0259876
• Length: 1351
• Species: Drosophila melanogaster
• Sequence 2: NP_001243134.2
• Gene: ncapg / 492707
• ZFINID: ZDB-GENE-041111-282
• Length: 1003
• Species: Danio rerio
• Alignment Length: 1112
• Identity: 268/1112 - (24%)
• Similarity: 463/1112 - (41%)
• Gaps: 245/1112 - (22%)

  Fly    61 QAELKESLHKRYSKEMQQLYAKMGHESFRKAFINVLK---AVLGAEEGNENA-NMALNFCATFVT 121
            :|:|..||...|:|...:       ..|.:.||..||   .:...|...||. :....|.|:|..
Zfish    23 KAKLVASLKNGYNKLEDK-------TQFHEEFIRCLKYAMIIYTREPAVENVIDFVTKFAASFEI 80

  Fly   122 SSDSDGTE--------PMLAETFHWLLTTYSSNPH-IRYRICYFVNLILKELGPNAALDDHQCDD 177
            ..:.:..|        ..|...|::||.::.:|.| :|:|:|..||.:|..|..||.:||..||.
Zfish    81 PVNEEAEEEEEEEEDNEFLNFLFNFLLESHGANSHAVRFRVCQLVNKLLGSLSENAQIDDDLCDR 145

  Fly   178 ILEAMLDRVKDVSASVRKQAVLAMQRLQNPDNPSDVVVGAYMYHLTSDPSPNVRQCIITCMGRNY 242
            |.||||.||.|...:||.||.|||.|||:|.|.....:.||:..|.:|.:|.||:.:::|:..:.
Zfish   146 IHEAMLVRVTDKYPNVRIQAALAMARLQDPTNSDCPTIKAYVLLLENDSNPEVRRAVLSCIAPSA 210

  Fly   243 ITIPHILERLWDVDEKVRRHTYVNMC-NYPVRSYKVAQRLTLLEQGLNDTSATVRKTVINFMLKT 306
            :|:|.|.:|..||.||||:..|..:. ...:|:..:|||::||.:||:|:|.:|::.|...:|..
Zfish   211 VTLPKIYKRTRDVKEKVRKLAYEVLAEKVHIRALSIAQRVSLLHEGLSDSSDSVKEVVRAHLLPA 275

  Fly   307 WIESYQQNYVALIAALKLDSNEEELLRFRRVAKQMLRVIFQQT----DIKQLIDQLPLSEDCELH 367
            |:...|.:.:.|:..|.:::..:       .|...|..||...    |:.|  :.:.|.|    .
Zfish   276 WLRLLQGDVLQLLHRLDVENCAD-------TAVTALHAIFSMATSPDDLMQ--NGVRLDE----R 327

  Fly   368 RCIPHDSVTVELLLYWQCLSEYLETEAPE----IESLLPELSVFCTYMDKF-------CQFQKPD 421
            :.||.:|:|.|.:|||:.|.|:::::..|    :|.||||.:::..|:..|       .:.|:.|
Zfish   328 KLIPVNSLTCENVLYWRALCEFVKSKGNEGEELLEQLLPEAAIYAEYLYSFLKSITQLSEAQRTD 392

  Fly   422 MDKFAQVEFQ----NMLLSLVEILETYDLGDEIGRGNMRLLITNLLKDCLLDHKIVRVLVRCMEQ 482
            |.:...|..|    ..|:.||..|:|   .:|.||..|..::..:|........::.:||..:..
Zfish   393 MTQLEMVMTQEFVGQQLILLVGCLDT---SEEGGRKRMVAVLQEILVMPNTPVSLIGLLVEKLVN 454

  Fly   483 LITDTNDRIQYFIEIIYEL-------------CELNTKQNDLIHDRSLINKLLDDLDTPLK---- 530
            ::.|...:||...|||.::             .|...||..|...|..|.:....|:..:.
Zfish   455 ILRDDAQKIQMVAEIISDVREPIFPISEPVDENEKRRKQVRLAEVRVQIMEAKQTLEDCISCQDF 519

  Fly   531 MKISSLKVKILELEELEGNYVRQREYIRAQSVNDEKIAVTEEYT---------ELIRPLLEKHGV 586
            .:.:.||..|.:||||: |.:.......|::|.:::|..::..|         ||.:.:..|.||
Zfish   520 SRAAELKDSISQLEELK-NQLTLEVSQPAENVKEQRIEKSDPETLLKCLTMCAELFKQMSIKRGV 583

  Fly   587 -------IEMPTRPKLSKQERVLKGLYISYYMTASPHVHKLTPSLCQLYKDFICRYLPCAEVDIF 644
                   ||....|.:|.....::.:.:....||:.|           .||....:|
Zfish   584 CPTMIALIESLILPSVSNPNPAVRNMAVICLGTAALH-----------SKDLANTHL-------- 629

  Fly   645 EWSIKCGTTFSIFYEAYSREVFEVVVVQFCKNNNVRLCEASANCILELLDRYGVDYFND-----L 704
                                   |:::|..:.:..::..::...:::.|...|:|...|     .
Zfish   630 -----------------------VLLLQITQLDEPKIRISALRSLIDQLLLNGLDILQDKPVPPT 671

  Fly   705 NQTGGSLSKTKRRQLYTMQELYDDDDGSQSQNNEQNSDILVVLGHYLE------RVQHRGVGMAI 763
            :||..|            .::.|.....|::.......||.:|..:|:      |.:       .
Zfish   672 SQTPDS------------PDISDRQPEKQAEEESPVQSILKMLSEFLDSEVCELRTE-------T 717

  Fly   764 VRGLCRLVLRGHVDDRTDVLELLLKRYFNPNTE--PIINQVLGLFFEELRRLNKHSLLQPC---- 822
            ..||.:|:..|.:.. ..:|..|:..::||.||  ..:...||:|.:...|.::.:  |.|
Zfish   718 AEGLAKLMYCGRILS-PKLLSRLVLLWYNPVTEDDQRLRHCLGVFLQLYARASRAN--QECVEES 779

  Fly   823 FLPTVWT---CNYDSPLHGVQPEHLTKFFLEMT-----VQEMSTPQTNIHNKIAISFLQYIQNYF 879
            ||||:.|   ....|||..|...::.:.|:|:|     ||.......::|:.:|:.....|
Zfish   780 FLPTMRTLFNAPVTSPLSEVDASNVAELFVELTRPSALVQPAVVQAVSVHDSLALRVCNEI---- 840

  Fly   880 TERKDM----CRLLAKELTNLSINVLNGPEVKAELLALAENLIQSELD---PRMIKCIQNFKLVV 937
              .:|:    .||..|.|:.|.||...|| ...||..|.::::|...|   .|:|:.:.|..:..
Zfish   841 --LRDVSAPEVRLYCKTLSWLEINTEPGP-ANNELQLLLKDILQEVKDKYCTRVIEKLCNQLIGD 902

  Fly   938 NGSFNPPPRRNPDEGESDEEYETATVTTAES--ETAVPAQSQPPVTEESPNDVTQSAAITAVDAT 1000
            :||            :|....:||.:...|:  |.....:::|...:..     |..|.||.:..
Zfish   903 HGS------------KSASNQDTALLNLDENNGELMNKDETKPKRAKRG-----QKKAATAKNGK 950

  Fly  1001 ETPKAAAPPAPVPEPIVTTFGKDNIVGIRHLRRSMAISHSDAESLLGPQ---SPNPEESTESEAV 1062
            ::.||                            .|:...||.|::  |:   |..|....:..|:
Zfish   951 KSYKA----------------------------DMSSDESDEENI--PEEAPSVRPSRRAKIAAL 985

  Fly  1063 ETSKQNL 1069
            :.:||:|
Zfish   986 DKTKQDL 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cap-G	NP_995827.2	YCG1	49..>526	CDD:227543	148/510 (29%)
		HEAT repeat	95..124	CDD:293787	8/32 (25%)
		HEAT repeat	134..163	CDD:293787	11/29 (38%)
		HEAT repeat	176..203	CDD:293787	16/26 (62%)
		HEAT repeat	214..240	CDD:293787	8/25 (32%)
		HEAT repeat	243..270	CDD:293787	11/27 (41%)
		Cnd3	603..898	CDD:463678	61/323 (19%)
		PRK07003	<960..>1174	CDD:235906	22/115 (19%)
ncapg	NP_001243134.2	None