DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13326 and PKP4

DIOPT Version :9

Sequence 1:NP_610838.1 Gene:CG13326 / 36439 FlyBaseID:FBgn0033794 Length:867 Species:Drosophila melanogaster
Sequence 2:NP_001364147.1 Gene:PKP4 / 8502 HGNCID:9026 Length:1192 Species:Homo sapiens


Alignment Length:357 Identity:74/357 - (20%)
Similarity:128/357 - (35%) Gaps:85/357 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   476 YSSLTEQLAQLLMRSFAHSILVNNIF--RCLCTLIDEAPVRETL------LANYIVSSMKRALKS 532
            |:|...||.|.|..:.:..:.:..|:  |...:.:..:|...|:      .|.|...|:     .
Human   390 YASQHSQLGQDLRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSV-----G 449

  Fly   533 LSNLVKTSV---------TNFILQTTRFNEFIDAY--IDRGIMEVLLDFQKHAFCI---STWGPA 583
            :.||.:||.         .|:.|.||.  .:.:.|  |...:.|...:..:||...   :|..|:
Human   450 IGNLQRTSSQRSTLTYQRNNYALNTTA--TYAEPYRPIQYRVQECNYNRLQHAVPADDGTTRSPS 512

  Fly   584 IESILSKCPTMKFAIRN----------CLTFTDITAGKDFYVSRRKFED------------FRKF 626
            |:|| .|.| .:||.|:          ...|..:.|....|:....|.|            .:..
Human   513 IDSI-QKDP-REFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHL 575

  Fly   627 QDIL--------RNDCSPL-DAVLVMNFDRPKPNQNDVIAVP--LRCL-----STITDLPGDQGW 675
            .|:|        :|.|..| :.|...:.|..|....:|..:|  ||.|     :.:.:|.....|
Human   576 VDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLW 640

  Fly   676 GY--CKRPGDNNLPQYLEALNQTLAMHGLVENPERVRRTIDFENVAK-RSKLIAQAVNAVMSENL 737
            ..  |.......:...|..|..|:    :|.:......:.|.::..| ::.|:.:.....:.   
Human   641 NLSSCDAVKMTIIRDALSTLTNTV----IVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLR--- 698

  Fly   738 KILDLNSTEECCRNTVR-CH--LQELRHVLHT 766
               :|:|..|..|..:| |.  :..|.:|:||
Human   699 ---NLSSAGEEARKQMRSCEGLVDSLLYVIHT 727

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13326NP_610838.1 EDR1 <759..799 CDD:291079 4/8 (50%)
PKP4NP_001364147.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..31
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 73..262
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 290..310
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 323..348
ARM 1 415..455 8/44 (18%)
ARM 2 518..557 8/39 (21%)
ARM 3 560..599 5/38 (13%)
ARM 4 604..644 9/39 (23%)
ARM 5 660..702 7/51 (14%)
ARM 6 706..751 7/22 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 773..810
ARM 7 815..855
ARM 8 862..901
ARM 9 950..993
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1058..1086
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2332
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.030

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