Protein Alignment CG13326 and Armc3

DIOPT Version :10

• Sequence 1: NP_610838.1
• Gene: CG13326 / 36439
• FlyBaseID: FBgn0033794
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_036018461.1
• Gene: Armc3 / 70882
• MGIID: 1918132
• Length: 885
• Species: Mus musculus
• Alignment Length: 1007
• Identity: 223/1007 - (22%)
• Similarity: 370/1007 - (36%)
• Gaps: 310/1007 - (30%)

  Fly    26 FTEVSVPIKKLDTALLLLSSKEECVLLTIFSHITDFARRQDVN---VLELKAHRLLELLLEKDLF 87
            |..:::..||..|.:|:|.|.||.:|......|..||.:.:.|   :|||.|...|..||
Mouse    17 FDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLL----- 76

  Fly    88 IASENTMIRRFALYLLTALLDNTD--------------MSTYEPEQADQILELACRFYMKEVDDF 138
             ..|:..:||.|:.:...|..|:|              ::...||:...|.|.|
Mouse    77 -THEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFA----------- 129

  Fly   139 CIEYLTYILNVCLKDPQMAHGIVEATEFLEKFK-------LVFISSENPDTVFNSIEALHRMLLV 196
                     ::||     |:..||.|..::.|:       :..:||.:||...||||.::.  ||
Mouse   130 ---------SLCL-----ANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYN--LV 178

  Fly   197 QSADQMLDF----TTQPDFPVDRIICEVTNEFQEIRKAALKTL---------KTLLADTG----- 243
            |      ||    |.|....:..|:..:.:|:..|:..|||||         :|:|.:..
Mouse   179 Q------DFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHL 237

  Fly   244 ---------DDSVFEALH---RCY-----FVLEQ----LVKV--FCESPQGPE-AADVIEVLATA 284
                     :|...|||.   .|.     .||.|    |.||  |.||...|: ..:..:.:|.|
Mouse   238 TKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKA 302

  Fly   285 LRSEKMTKLFFEQNLFDQVVEQVRNHMDLMPLEMRCTIISIFAETAQYEQF-----LPRM----- 339
            ....:..|:|.||.:...:|..:.:..|...: .....||...|....::|     :|::
Mouse   303 AYDPENRKVFHEQEVEKCLVTLLGSDSDGTKI-AASQAISALCENLSCKEFFNTQGIPQIVQLLR 366

  Fly   340 ----HKAEIADMFLTCLMQNKPAPAAYVIQGLHRMSHHPEALRRIVAAYQEGAIRKLVAIL--MS 398
                ...|.|.:.|..|..:.||.|....:     :...:.|..|:::.::|||.....:|  |:
Mouse   367 SDNEEVREAAALALANLTTSSPANANAAAE-----ADAIDPLINILSSKRDGAIANAATVLTNMA 426

  Fly   399 PDVAIKAREQAGEFLSRLL-----------------VAAFR---ETAAQLQEQDIAVVL------ 437
            ....::|..|..|.:..||                 |||..   |...||:.....|.|
Mouse   427 TQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHS 491

  Fly   438 -----------TAVIAQGQPTLSIDLILL-LLTIIE----SLAQKEE-----YRTILGEYSSLTE 481
                       ..::..|...::::|..| .|.|:|    ||::|.:     |..:|....||..
Mouse   492 KNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKY 556

  Fly   482 QLAQLLMRSFAHSILVNNIF----------------RCLCTLIDEAPVRETLLANYIVS-----S 525
            .....|..|   :|:.:..:                .||..|.|:   |..||.|....     |
Mouse   557 SQTGYLSSS---NIISDGFYDYGRINPGTKLLSLKELCLQELNDQ---RAILLVNNKSDTSPPPS 615

  Fly   526 MK---------RALKSLSNLVKTS--VTNFILQTTRFNEFIDAYIDRGIMEVLLDFQKHAFCIST 579
            |:         |::.|.|:|.:.|  ..||     ||:                         :.
Mouse   616 MEDKSSDVGYGRSISSSSSLRRGSKEKANF-----RFS-------------------------AI 650

  Fly   580 WGPAIESILSKCPTMKFAIRNCLTFTDITAGKDFYVSRRKFEDFRKFQDILRNDCSPLDAVLVMN 644
            :|...|.     .:...::||.:.....|  |:..||::|..        |:..||   :.|:..
Mouse   651 FGSPTEE-----KSEPASVRNTILSRAFT--KEKGVSKKKSR--------LQLICS---SYLLWK 697

  Fly   645 FDRPK-----PNQNDVIAVPLRCLSTITDLPGDQGWGYCKRPGDNNLPQY-LEALNQTLAMHGLV 703
            ....|     ..:.:::|:|     ..|:...::.|   ..|.|.....| ||.....|.:..|.
Mouse   698 GKGKKEEEKVKEEEEILALP-----KFTEGSPEKEW---NPPPDPEFCVYVLEVTKSILPIVNLK 754

  Fly   704 ENPERVRRTIDFENVAKRSKLIAQAVNAVMSENLKILDLNSTEECCRNTVRCHLQELRHVLHTNF 768
            |..|.:            :|.:|..:...:.:. |:.|.         :...|:.||:..|.:|.
Mouse   755 EQIEVL------------AKYVADKMGGKIPKE-KLADF---------SWELHISELKFQLKSNV 797

  Fly   769 IPLGMVRSGCQFERAILFKGLADQIGLPCTLQRSVDGRMLYNELPLPLEPEKDVHCDKKTLKYMP 833
            :|:|.::.|..:.||:|||.|||:||:.|:|.|....|. :||:.|..|..|.:      :..:|
Mouse   798 VPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRG-WNEVKLVNEARKGM------IGNLP 855

  Fly   834 WRMLRP--THVVDLLYNVGELYPMQSRQALQY 863
                 |  .::|||:::.|.|..::|::|..|
Mouse   856 -----PPEEYIVDLMFHPGNLLKLRSKEADLY 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13326	NP_610838.1	EDR1	<758..799	CDD:433922	18/40 (45%)
Armc3	XP_036018461.1	armadillo repeat	22..52	CDD:293788	10/29 (34%)
		armadillo repeat	60..96	CDD:293788	12/41 (29%)
		HEAT	62..216	CDD:441023	48/192 (25%)
		armadillo repeat	104..136	CDD:293788	8/56 (14%)
		armadillo repeat	143..177	CDD:293788	9/35 (26%)
		armadillo repeat	184..218	CDD:293788	10/33 (30%)
		armadillo repeat	225..259	CDD:293788	6/33 (18%)
		armadillo repeat	319..343	CDD:293788	4/24 (17%)
		armadillo repeat	350..385	CDD:293788	6/34 (18%)
		SRP1	<358..>504	CDD:227396	28/150 (19%)
		armadillo repeat	391..425	CDD:293788	7/38 (18%)
		ARM	469..504	CDD:214547	5/34 (15%)
		armadillo repeat	473..503	CDD:293788	4/29 (14%)
		EDR1	<754..871	CDD:433922	39/150 (26%)