DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13326 and ctnnb1

DIOPT Version :9

Sequence 1:	NP_610838.1	Gene:	CG13326 / 36439	FlyBaseID:	FBgn0033794	Length:	867	Species:	Drosophila melanogaster
Sequence 2:	NP_001016958.1	Gene:	ctnnb1 / 549712	XenbaseID:	XB-GENE-487200	Length:	781	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	88/442 - (19%)
Similarity:	150/442 - (33%)	Gaps:	130/442 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 PDTVFNSIEALHRMLLVQSADQMLDFTTQPDFPVDRIICEVTN--EFQEIRKAALKTLKTLLADT 242
            |.|.|:|....:...|.:.: |||          ...:..:.|  :..|:...|:..|..||.|
Frog   110 PSTQFDSAHPTNVQRLAEPS-QML----------KHAVVNLINYQDDAELATRAIPELTKLLND- 162

  Fly   243 GDDSVFEALHRCYFVLEQLVKVFCESPQGPEAADVIEVLATALRSEKMTKLFFEQNLFDQVVEQV 307
             :|.|  .:::...::.||.|        .||:     ....:||.:|.         ..:|..:
Frog   163 -EDQV--VVNKAAVMVHQLSK--------KEAS-----RHAIMRSPQMV---------SAIVRTM 202

  Fly   308 RNHMDLMPLEMRCT-------------IISIFAETAQYEQFLPRMHKAEIADMFLTCLMQNKPAP 359
            :|..|:.  ..|||             :::||....     :|.:.|           |...|..
Frog   203 QNTNDVE--TARCTAGTLHNLSHHREGLLAIFKSGG-----IPALVK-----------MLGSPVD 249

  Fly   360 AA--YVIQGLHRMSHHPEALRRIVAAYQEGAIRKLVAILMSPDVAIKAREQAGEFLS----RLLV 418
            :.  |.|..||.:..|.|..:  :|....|.::|:||:|...:|         :||:    .|.:
Frog   250 SVLFYAITTLHNLLLHQEGAK--MAVRLAGGLQKMVALLNKTNV---------KFLAITTDCLQI 303

  Fly   419 AAFRETAAQLQEQDIAVVLTAVIAQGQP--------TLSIDLIL----LLLTIIESLAQKEEYRT 471
            .|:....::|          .::|.|.|        |.|.:.:|    .:|.::...:..:....
Frog   304 LAYGNQESKL----------IILASGGPQALVNIMRTYSYEKLLWTTSRVLKVLSVCSSNKPAIV 358

  Fly   472 ILGEYSSLTEQLAQLLMRSFAHSILVNNIFRCLCTLIDEAPVRE----------TLLANYIVSSM 526
            ..|...:|...|.....|      ||.|....|..|.|.|..:|          .||.:..::.:
Frog   359 EAGGMQALGLHLTDSSQR------LVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVV 417

  Fly   527 KRALKSLSNLVKTSVTN--FILQTTRFNEFIDAYIDRGIMEVLLDFQKHAFC 576
            ..|...||||...:..|  .:.|.......:...:..|..|   |..:.|.|
Frog   418 TCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDRE---DITEPAIC 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13326	NP_610838.1	EDR1	<759..799	CDD:291079
ctnnb1	NP_001016958.1	armadillo repeat	153..178	CDD:293788	6/28 (21%)
		armadillo repeat	188..221	CDD:293788	9/43 (21%)
		PLN03200	216..>661	CDD:215629	57/297 (19%)
		armadillo repeat	230..262	CDD:293788	10/47 (21%)
		ARM	230..262	CDD:214547	10/47 (21%)
		armadillo repeat	270..306	CDD:293788	10/46 (22%)
		armadillo repeat	312..347	CDD:293788	8/44 (18%)
		ARM	350..390	CDD:214547	9/45 (20%)
		armadillo repeat	354..389	CDD:293788	8/40 (20%)
		armadillo repeat	402..427	CDD:293788	5/24 (21%)
		armadillo repeat	435..473	CDD:293788	6/35 (17%)
		armadillo repeat	482..517	CDD:293788
		armadillo repeat	524..582	CDD:293788
		Arm	583..622	CDD:366143
		armadillo repeat	587..621	CDD:293788
		armadillo repeat	629..662	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2332
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030