DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13326 and Odad2

DIOPT Version :9

Sequence 1:	NP_610838.1	Gene:	CG13326 / 36439	FlyBaseID:	FBgn0033794	Length:	867	Species:	Drosophila melanogaster
Sequence 2:	XP_038952403.1	Gene:	Odad2 / 307036	RGDID:	1306933	Length:	1073	Species:	Rattus norvegicus

Alignment Length:	869	Identity:	165/869 - (18%)
Similarity:	290/869 - (33%)	Gaps:	261/869 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PDRTKSEEKSFTEVSVPIKKLDTALLLLSSKEECVLLTIFSHITDFARRQDVNVL--ELKAHRLL 78
            ||..:.:|:| |.:::    |||   ::..||    |.|...:....::.|:::|  .|| |..|
  Rat   176 PDYDEMKEES-TSLAL----LDT---IIKDKE----LYIKRKVAILLKQLDLHLLNHSLK-HISL 227

  Fly    79 ELLLEKDLFIASENTMIRRFALYLLTALLDNTD-MSTYEPEQA------DQILELACRFYMK--E 134
            |:.|....| ..:..:::||:......:|:..: .|.||....      .||....|...:|  :
  Rat   228 EISLNPGTF-KKDIELLKRFSGKGEQTVLEWIEYTSDYEFSNGCRAPPWRQIQGEMCYVMVKPHD 291

  Fly   135 VDDFCIEYLT--YILN-----------------------VCLKD------PQMAHGIVEATEFLE 168
            |:..|:...|  ..||                       .||||      ..|:...:...|..:
  Rat   292 VETLCLTCSTEGVFLNGGKTEEEGAIDYERKGEVYKDIVTCLKDQSPVFSENMSKQEIRFNEEQQ 356

  Fly   169 KFKLVF---ISSENPDTVFNS----IEALH--RMLLVQSADQMLDFTTQPDFPVDRIICEVTNEF 224
            |...:|   .:.:.|.:...|    :|.|:  :..:.:..:..|::....|:...:   ..|.:.
  Rat   357 KDSQIFEKPKTEDGPSSATGSEKSKVEKLYFGKSHMTKRLEPSLNWRATVDYKDHK---SSTKDS 418

  Fly   225 QEIRKAALKTLKT-------LLADTGDDSVFEAL---------------HRC---------YFVL 258
            ||.::..|:...|       .|...|.:.|.|.:               ||.         |:.:
  Rat   419 QEEKQGKLEKSSTSVSTGRGQLLRKGGEKVEETVSESSSESEEDEEPLDHRQEANADLPSEYWQI 483

  Fly   259 EQLVKVFCESPQGPEAADVIEVLATALRSEKMTKLFFEQNLFDQVVEQVRNHMDLMPL----EMR 319
            ::|||..   ..|.:.|.||.:.:       |......|......:..|.....|:.|    |::
  Rat   484 QKLVKYL---KGGNQTATVIALCS-------MRDFNLAQETCQLAIRDVGGLEVLINLLDTDEVK 538

  Fly   320 CTI--ISIFAETAQYEQF---------LPRM-------HKAEIADMFLTCLMQNKPAPAAYVIQG 366
            |.|  :.|..|.:...|.         ||.|       ||:      |.||       ||..|..
  Rat   539 CKIGSLKILKEISHNPQIRRNIVDLGGLPIMVNILDSSHKS------LKCL-------AAETIAN 590

  Fly   367 LHRMSHHPEALRRIVAAYQEGAIRKLVAILMSPDVAIKAREQAGEFLSRLLVAAFRETAAQLQEQ 431
            :.:......|:|      |.|.|.||||:|   |....:.|.|...|              .:.:
  Rat   591 VAKFKRARRAVR------QHGGITKLVALL---DCGQNSSEPAQPGL--------------YETR 632

  Fly   432 DIAVVLTAVIAQGQPTLSIDLILLLLTIIESLAQKEEYRTILGEYSSLTEQLAQLLMRSFAHSIL 496
            |:.|.....:|             |.:..:|.:.||..|...|     ...||:||..|..:.::
  Rat   633 DVEVARCGALA-------------LWSCSKSHSNKEAIRKAGG-----IPLLARLLKTSHENMLI 679

  Fly   497 --VNNIFRCLCTLIDEAPVRETLLANYIVSSMKRALKSLSNLVKTSVTNFILQTTRFNEFIDAYI 559
              |..:..|    ..|...|..:.|..|:.::.:.|.|.:..::......|.|.....|..|...
  Rat   680 PVVGTLQEC----ASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDEETRDLVR 740

  Fly   560 DRGIMEVLLDF-----QKHAFCISTWGPAIESILSKCPTMKFAIRNCLTFTDITAGKDFYVSRRK 619
            ..|.::.|...     .|....      |:...:.||...|   .|.:                |
  Rat   741 LHGGLKPLASLLNNTDNKERLA------AVTGAIWKCSISK---ENVI----------------K 780

  Fly   620 FEDFRKF-----------QDILRNDCSPL--------DAVLVMNFDRPKPNQNDVIAVPLRCLST 665
            |.:::..           :::|.|....|        :.|||......:|..|.::.:....|..
  Rat   781 FREYKAIETLVGLLTDQPEEVLVNVVGALGECCQEYENRVLVRKCGGIQPLVNLLVGINQALLVN 845

  Fly   666 ITDLPGDQGWGYCKRPGDNNLPQYLEALNQTLAMHGLVENPE-RVRRTIDF------ENVAKRSK 723
            :|     :..|.|....::  ...::.|:....:..|::||. .|:.:..:      ||.....:
  Rat   846 VT-----KAVGACAVEPES--MAIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIENAKDAGE 903

  Fly   724 LIAQ-------AVNAVMSENLKIL 740
            ::..       .||.:.|:|.::|
  Rat   904 MVRSFVGGLELVVNLLKSDNKEVL 927

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13326	NP_610838.1	EDR1	<759..799	CDD:291079
Odad2	XP_038952403.1	PLN03200	<478..713	CDD:215629	65/302 (22%)
		armadillo repeat	483..508	CDD:293788	8/34 (24%)
		armadillo repeat	518..550	CDD:293788	7/31 (23%)
		armadillo repeat	557..593	CDD:293788	11/48 (23%)
		PLN03200	<599..>891	CDD:215629	67/368 (18%)
		armadillo repeat	600..646	CDD:293788	18/81 (22%)
		armadillo repeat	656..688	CDD:293788	8/36 (22%)
		armadillo repeat	694..731	CDD:293788	7/36 (19%)
		armadillo repeat	736..769	CDD:293788	5/38 (13%)
		armadillo repeat	778..814	CDD:293788	5/51 (10%)
		SRP1	<786..1071	CDD:227396	24/149 (16%)
		armadillo repeat	859..896	CDD:293788	5/38 (13%)
		armadillo repeat	912..937	CDD:293788	5/16 (31%)
		armadillo repeat	944..1021	CDD:293788
		HEAT repeat	955..983	CDD:293787
		armadillo repeat	1027..1060	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910