DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13326 and ctnnb1

DIOPT Version :9

Sequence 1:	NP_610838.1	Gene:	CG13326 / 36439	FlyBaseID:	FBgn0033794	Length:	867	Species:	Drosophila melanogaster
Sequence 2:	XP_005157888.1	Gene:	ctnnb1 / 30265	ZFINID:	ZDB-GENE-980526-362	Length:	789	Species:	Danio rerio

Alignment Length:	402	Identity:	81/402 - (20%)
Similarity:	145/402 - (36%)	Gaps:	121/402 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 PDTVFNSIEALHRMLLVQSADQMLDFTTQPDFPVDRIICEVTN--EFQEIRKAALKTLKTLLADT 242
            |.|.|:|....:...|.:.: |||          ...:..:.|  :..|:...|:..|..||.|
Zfish   109 PSTQFDSAHPTNVQRLAEPS-QML----------KHAVVNLINYQDDAELATRAIPELTKLLND- 161

  Fly   243 GDDSVFEALHRCYFVLEQLVKVFCESPQGPEAADVIEVLATALRSEKMTKLFFEQNLFDQVVEQV 307
             :|.|  .:::...::.||.|        .||:     ....:||.:|.         ..:|..:
Zfish   162 -EDQV--VVNKAAVMVHQLSK--------KEAS-----RHAIMRSPQMV---------SAIVRTM 201

  Fly   308 RNHMDLMPLEMRCT-------------IISIFAETAQYEQFLPRMHKAEIADMFLTCLMQNKPAP 359
            :|..|:.  ..|||             :::||....     :|.:.|           |...|..
Zfish   202 QNTNDVE--TARCTSGTLHNLSHHREGLLAIFKSGG-----IPALVK-----------MLGSPVD 248

  Fly   360 AA--YVIQGLHRMSHHPEALRRIVAAYQEGAIRKLVAILMSPDVAIKAREQAGEFLS----RLLV 418
            :.  |.|..||.:..|.|..:  :|....|.::|:||:|...:|         :||:    .|.:
Zfish   249 SVLFYAITTLHNLLLHQEGAK--MAVRLAGGLQKMVALLNKTNV---------KFLAITTDCLQI 302

  Fly   419 AAFRETAAQLQEQDIAVVLTAVIAQGQPTLSIDLI-------LL-----LLTIIESLAQKEEYRT 471
            .|:....::|          .::|.|.|...::::       ||     :|.::...:..:....
Zfish   303 LAYGNQESKL----------IILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIV 357

  Fly   472 ILGEYSSLTEQLAQLLMRSFAHSILVNNIFRCLCTL--IDEAPVRETLLANY-IVSSMKRALKSL 533
            ..|...:|...|.....|      ||.|   ||.||  :.:|..::|.||.. :...|:..|.:|
Zfish   358 EAGGMQALGLHLTDPSQR------LVQN---CLWTLRNLSDAATKQTSLAEVDVQEGMEGLLGTL 413

  Fly   534 SNLVKTSVTNFI 545
            ..|:.:...|.:
Zfish   414 VQLLGSDDINVV 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13326	NP_610838.1	EDR1	<759..799	CDD:291079
ctnnb1	XP_005157888.1	ARM	<151..221	CDD:237987	21/97 (22%)
		armadillo repeat	152..177	CDD:293788	6/28 (21%)
		armadillo repeat	187..220	CDD:293788	9/43 (21%)
		ARM	228..347	CDD:237987	30/155 (19%)
		armadillo repeat	229..261	CDD:293788	10/47 (21%)
		armadillo repeat	269..305	CDD:293788	10/46 (22%)
		armadillo repeat	311..346	CDD:293788	7/44 (16%)
		ARM	349..389	CDD:214547	11/48 (23%)
		armadillo repeat	353..389	CDD:293788	11/44 (25%)
		ARM	407..526	CDD:237987	4/19 (21%)
		armadillo repeat	410..435	CDD:293788	4/16 (25%)
		armadillo repeat	443..481	CDD:293788
		armadillo repeat	490..525	CDD:293788
		ARM	492..631	CDD:237987
		armadillo repeat	532..590	CDD:293788
		armadillo repeat	595..629	CDD:293788
		ARM	597..>676	CDD:237987
		armadillo repeat	637..670	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2332
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940