DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and CG17707

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001162627.1	Gene:	CG17707 / 5740408	FlyBaseID:	FBgn0025835	Length:	990	Species:	Drosophila melanogaster

Alignment Length:	804	Identity:	157/804 - (19%)
Similarity:	293/804 - (36%)	Gaps:	223/804 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 QLRSLGIEFTEYFRNIST-----------QDLGGLESQFSSEDDLL-----------------CL 71
            |:::||.......|.:.|           :.|.|..:.|....:|.                 |.
  Fly   216 QIKTLGSTINSIHRYLGTTANGTGNGTAVESLYGQANYFQLVANLYDHFYWQISEIRTNVHTGCG 280

  Fly    72 NDMKALMTGLGSAEYWALKMIDAWGSIPSGLLAGNSYDLGNFDECLNI-RKEIGQERT-IQGKYC 134
            .:|:|.:|.|.|:..||.|..|:.|.....||.||...||....|..: |:.:.:||. ...::.
  Fly   281 LEMQAYLTALHSSYEWAQKAYDSSGRYRGQLLFGNDKWLGQLSFCYELNRQSLTEERQHFDLQFY 345

  Fly   135 FLSVS---PAKILGIETSIGSFRTATCFPASCSAINMNAFVDQLMMKLLNVSVPSSAMRISEGSC 196
            ...|:   |:....:..|:|.     |.|.|||.|::.:        :|::. |.:.|....|:.
  Fly   346 VADVALHLPSLNRSMLLSLGE-----CLPKSCSDIDVKS--------ILSLD-PYARMLTVLGAH 396

  Fly   197 QTSDSEP----------------WD----------ALTIFMIVILS------------LMSFIVA 223
            .||..:|                |.          .||:|::::::            :::.|.|
  Fly   397 NTSMQQPPLQILHVRTVPGIYSHWRQLKFQVFISFMLTLFLVILVASYYQLKIDERRLVVAPIAA 461

  Fly   224 L---------------------------------------------------------------- 224
            :
  Fly   462 ISGKCDGTSTKNDVFYGKSFELFQMRPLGCTSSSTDDPEVDVNGNRQRCGDSSDMENGVQREFAD 526

  Fly   225 ----------STLWDY-------------FLVKDQDQLPAIVKICSA-RSNSRALFRV---VESH 262
                      |.:.||             :..|....|...:.:|.| ::|::|:..:   .|.|
  Fly   527 PNTSTSVGEKSEMGDYQMETGSCAGGTGTYEAKQSVALHQQILLCFALQTNAKAILNINKTKEIH 591

  Fly   263 SNPNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEKPFASFILHGFISVDSFLVI 327
            :     .||||:|..|::|.:..|.| :.:.:...|.|.........:...|.:...|||||..|
  Fly   592 T-----ACLHGLRVFSVLWTMMVHTY-LQMFAIGENKFERIITERSFWYQVIGNATFSVDSFFFI 650

  Fly   328 GGLLVALIPLRLMDK--TKGKLNVP-------MMYLHRLIRIAPLLAMAIVVHMKLMPLISSGPL 383
            .||||.::.|:...|  |:..|.:.       ||.|:|.:|:.|:....::.:...:.......:
  Fly   651 SGLLVTMLYLKQNRKYPTETCLFIKSCFSESLMMLLYRYLRLTPVYLFVVIFNDFAVRQGLDTSV 715

  Fly   384 FVGGYIGNSACKAGWYWTLLFVNNY--TDAKCLAQSWYLSLDMQLYIISPILLISLYKWGKKAAA 446
            |....|.::.|:..|:..:|::|||  ....|:..|||::.:||.|:::.:||....|:.|  |.
  Fly   716 FQPAKIEHNTCRMYWWRNILYINNYFPQTEMCMMWSWYMANEMQFYVMAALLLALARKYFK--AV 778

  Fly   447 GIFILIILLSACLFATMMVNGYSMMITAASPEAMRDGYYATHTHATPW------LIGFLFGYFLH 505
            .|.:.:.|||:...:.::...|......:.|....|..|     ..||      ::|...||.|:
  Fly   779 AITLFVFLLSSWSISGIISLTYQYTHKVSLPFESFDFLY-----DKPWQRVGSYIMGMCTGYVLY 838

  Fly   506 LNR-----GKKFQLSWVSVWSGWILCLAMIFTSIFALYPPSKWSDPDASTLAESFYYTLTRVGWA 565
            ..:     .::..||.      |...|.::...:|.::      :....|.:.:||..:....:.
  Fly   839 KVKTPPLISRRLNLSL------WACSLFVLLIVVFGVW------EGHLGTTSSAFYVGVAHTAFG 891

  Fly   566 LALCWVIFACVQGYGGLANSFLASPLWQPLSRLSYSVFIWHMFFMEMNARSTRTSTYFSDYGMML 630
            ..|.|::.:|..|.....|:.|:..:..|||||:|..::.|...|.:.:.....:.:.|:..::.
  Fly   892 CGLVWIVLSCCWGLVPTVNAILSYRVMWPLSRLTYCAYLIHPIIMFICSSHMSGTVHLSNPLILT 956

  Fly   631 NFWSTLGFTLLFSYAMHLLIEAPI 654
            .|......:...::.:....|||:
  Fly   957 LFLGNAVVSFGCAFVISAFFEAPV 980

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	29/117 (25%)
		Acyl_transf_3	268..648	CDD:280013	90/401 (22%)
		OafA	299..654	CDD:224748	82/376 (22%)
CG17707	NP_001162627.1	NRF	294..399	CDD:214781	29/118 (25%)
		Acyl_transf_3	595..973	CDD:280013	89/397 (22%)
		OafA	597..985	CDD:224748	90/404 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	6	5.920