DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and CG16723

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_651159.3	Gene:	CG16723 / 42781	FlyBaseID:	FBgn0039092	Length:	695	Species:	Drosophila melanogaster

Alignment Length:	700	Identity:	388/700 - (55%)
Similarity:	501/700 - (71%)	Gaps:	34/700 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTNQVIVFLLCGFVIISAGNPNSDDVLPQFRNVRQLRSLGIEFTEYFRNISTQDLGGLESQFSSE 65
            |.|.|.|.|..|.|...|......||...:..:.|||.||:||.|:|:|::.:.||..:|:.:|.
  Fly     1 MVNVVGVLLFYGLVATCALELTDPDVSKTYEYISQLRPLGLEFAEFFKNVTLESLGVSDSKLASA 65

  Fly    66 DDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPSGLLAGNSYDLGNFDECLNIRKEIGQERTIQ 130
            :|.||..::.|:|.|:...|.|||||||||||||:|||.||.:|||||||||:|.|.:|.:| |:
  Fly    66 EDELCSVELAAVMNGISLRETWALKMIDAWGSIPNGLLTGNLFDLGNFDECLSIEKVVGGKR-IR 129

  Fly   131 GKYCFLSVSPAKILGIETSIGSFRTATCFPASCSAINMNAFVDQLMMKLLNVSVPSSAMRISEGS 195
            ||:|||..:.|:|            |||||||||:..|..||:|| |.|:|::..|..||||..|
  Fly   130 GKFCFLLANSARI------------ATCFPASCSSTQMETFVEQL-MALINLNSSSLKMRISGAS 181

  Fly   196 CQTSDSEPWDALTIFMIVILSLMSFIVALSTLWDYFLVKDQDQLPAIVKICSARSNSRALFRVVE 260
            ||||:.|||:.||||.|||||||..||...|::||||..|...:||:||..|||:|||||||:|.
  Fly   182 CQTSEIEPWNGLTIFTIVILSLMCVIVISVTIFDYFLCDDPRSIPAVVKTFSARANSRALFRIVP 246

  Fly   261 SHSNPNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEKPFASFILHGFISVDSFL 325
            :.||||||:|.||||||:|.|||.||::...|.||::|.....||..|||:||:|||:.:||||.
  Fly   247 NKSNPNVIECFHGIRCMTLFWVIYCHEFIFFLTSPNLNRLDLYTWTVKPFSSFVLHGYFAVDSFF 311

  Fly   326 VIGGLLVALIPLRLMDKTKGKLNVPMMYLHRLIRIAPLLAMAIVVHMKLMPLISSGPLFVGGYIG 390
            |:|||||::|.||.|:|:.|:||..:|||||::||.|::|:||:::|.:|.::|.||:...||.|
  Fly   312 VLGGLLVSMISLRSMEKSGGRLNPVLMYLHRILRILPVVAIAILIYMTMMTVVSGGPMLKNGYHG 376

  Fly   391 NSACKAGWYWTLLFVNNYTDAK-CLAQSWYLSLDMQLYIISPILLISLYKWGKKAAAGIFILIIL 454
            ...|..||:|||||:.||.... ||..:|||::||||:|||||||::||.||||||:||.:|::|
  Fly   377 MEYCLNGWFWTLLFIQNYAVQNICLDHTWYLAVDMQLFIISPILLMALYNWGKKAASGIAVLVVL 441

  Fly   455 LSACLFATMMVNGYSMMITAASPEAMRDG---------YYATHTHATPWLIGFLFGYFLHLNRGK 510
            ||.|||||.|||.|:::|      .:.||         |.||||||.|||||||||||||:||||
  Fly   442 LSGCLFATQMVNHYTLLI------KINDGDDGVPNKKLYLATHTHAAPWLIGFLFGYFLHINRGK 500

  Fly   511 KFQLSWVSVWSGWILCLAMIFTSIFALYPPSKWSDPDASTLAESFYYTLTRVGWALALCWVIFAC 575
            |||||...||.||||.|||:|||||||||.|:.:.|..|||.||.||||||:.|.||:||:||||
  Fly   501 KFQLSRPIVWLGWILSLAMLFTSIFALYPASQLTAPPLSTLEESLYYTLTRLAWPLAICWIIFAC 565

  Fly   576 VQGYGGLANSFLASPLWQPLSRLSYSVFIWHMFFMEMNARSTRTSTYFSDYGMMLNFWSTLGFTL 640
            :|||||||||||::||||||||||||::|||||..|:|:|:.||:|||::|..|..|...||||:
  Fly   566 MQGYGGLANSFLSTPLWQPLSRLSYSMYIWHMFVQEVNSRNVRTNTYFTNYIAMERFCYDLGFTV 630

  Fly   641 LFSYAMHLLIEAPIGGLDIFLRPKGKISPTEKQTSHIDDK---EPRDPEN 687
            |.||.::|:||||:.|.|..||.: |..|...:.:.|.::   |.||||:
  Fly   631 LMSYILYLIIEAPLCGFDSILRGR-KDPPAPNKANIISNERGMENRDPED 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	64/112 (57%)
		Acyl_transf_3	268..648	CDD:280013	232/389 (60%)
		OafA	299..654	CDD:224748	218/364 (60%)
CG16723	NP_651159.3	NRF	87..184	CDD:214781	63/110 (57%)
		Acyl_transf_3	254..599	CDD:280013	213/350 (61%)
		OafA	291..644	CDD:224748	217/358 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458044
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	12	11.800