DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and CG5892

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_650959.2	Gene:	CG5892 / 42522	FlyBaseID:	FBgn0038873	Length:	738	Species:	Drosophila melanogaster

Alignment Length:	721	Identity:	323/721 - (44%)
Similarity:	464/721 - (64%)	Gaps:	35/721 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTNQVIVFLLCGFVIISA---------GNP-NSDDVLPQFRNVRQLRSLGIEFTEYFRNISTQDL 55
            |....:|.|:.|..:.||         ||. ::.|    ::.:.::|.|..:|..|::|::..||
  Fly     1 MAKVSVVVLILGLAVTSALDFGPEINEGNELDAQD----YQRLNKVRHLSEQFFSYYKNVTLDDL 61

  Fly    56 GGLESQFSSEDDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPSGLLAGNSYDLGNFDECLNIR 120
            .. |.:..:..||.|..|...|..||.|...||.:|||:|||||||:|.|:..|||::|||:.|.
  Fly    62 VP-EGRLPTVSDLQCYADFAQLTAGLASGSLWAYRMIDSWGSIPSGILKGHLKDLGHYDECIAIE 125

  Fly   121 KEIGQERTIQGKYCFLSVSPAKILGIETSIGSFRTATCFPASCSAINMNAFVDQLMMKLLNVSVP 185
            :......|:.||||..|:...::||....:.:.:||.||||||||.||:..:.:::.:|:.:.:.
  Fly   126 QSAASGSTLLGKYCLASLPLQQLLGNVGRMMNVQTAVCFPASCSATNMDTLLRRVLKQLVGLELN 190

  Fly   186 SSAMRISEGSCQTSDSEPWDALTIFMIVILSLMSFIVALSTLWDYFLVKDQDQLPAIVKICSARS 250
            |:...:||.||:||:.:.:|...|..|||||:....|.:||.:||||..||::||||:|:.|||:
  Fly   191 SNQNLVSENSCKTSERDAYDGGAIAAIVILSVFGGAVIISTFYDYFLCADQNKLPAILKVFSARA 255

  Fly   251 NSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEKPFASFIL 315
            |||:|||:. :..|||||:||||:|.||||||...|.:.:::.||:|||:...||.:.||...|.
  Fly   256 NSRSLFRIT-TKPNPNVIECLHGLRGMSLIWVCFGHDFIISMTSPNINLYDVYTWAKTPFKDIIQ 319

  Fly   316 HGFISVDSFLVIGGLLVALIPLRLMDKTKGKLNVPMMYLHRLIRIAPLLAMAIVVHMKLMPLISS 380
            .|..:||||..|.|||||::.||.|:|.|||||:|:|||||.:|:.|::|::|:::.||:|.:..
  Fly   320 EGVFAVDSFFFISGLLVAMVALRSMEKAKGKLNIPLMYLHRYLRLTPIVAVSILLYWKLLPHLGD 384

  Fly   381 GPLFVGGYIGN------SACKAGWYWTLLFVNNY-TDAKCLAQSWYLSLDMQLYIISPILLISLY 438
            |||:     ||      ..|:..||||||:|.|| ||::|||.:|||::|.|||||:|||||.:|
  Fly   385 GPLY-----GNWNFDSYDRCEGNWYWTLLYVQNYATDSECLAHTWYLAIDTQLYIIAPILLIIVY 444

  Fly   439 KWGKKAAAGIFILIILLSACLFATMMVNGYSMMITAAS---PEAMRDGYYATHTHATPWLIGFLF 500
            |||||.||.:.:|::.|:|.||:.:::|.||::.....   .:...|..:.||..|:.||:||||
  Fly   445 KWGKKGAAVVLLLLLGLTAYLFSIIVINNYSLISGGGGGGPDDYSEDLDHYTHNRASGWLVGFLF 509

  Fly   501 GYFLHLNRGKKFQLSWVSVWSGWILCLAMIFTSIFALYPPSKWSDPDASTLAESFYYTLTRVGWA 565
            |||||..|||..:||..:||.|||.|||.:||.|||:||..........||.|:||.:|:|:.|.
  Fly   510 GYFLHTIRGKAIKLSRPAVWIGWITCLAFLFTCIFAMYPYGTGKSKTLPTLNEAFYVSLSRIAWP 574

  Fly   566 LALCWVIFACVQGYGGLANSFLASPLWQPLSRLSYSVFIWHMFFMEMNARSTRTSTYFSDYGMML 630
            |.|.||:|||:|||||||||||.||||||||:||:..::.|:|...:||..||.:||||:|.:||
  Fly   575 LGLSWVVFACMQGYGGLANSFLTSPLWQPLSKLSFCAYMGHLFIQNLNAGRTRVNTYFSNYDIML 639

  Fly   631 NFWSTLGFTLLFSYAMHLLIEAPIGGLDIFLRPKGKISPTEKQTSHIDDKE----PRDPENLLEP 691
            .||...|||:|.:|.|::|||||.|||:..:.|..:.:|..|..:....||    |.|.|.....
  Fly   640 RFWQDFGFTVLLAYVMYILIEAPCGGLESLILPNRRPAPQPKVQAAEPSKEEIPSPVDLEKQTPE 704

  Fly   692 TTSTVD 697
            :::.:|
  Fly   705 SSAAID 710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	47/112 (42%)
		Acyl_transf_3	268..648	CDD:280013	198/389 (51%)
		OafA	299..654	CDD:224748	185/364 (51%)
CG5892	NP_650959.2	NRF	90..203	CDD:214781	47/112 (42%)
		Acyl_transf_3	272..656	CDD:280013	197/388 (51%)
		OafA	277..685	CDD:224748	205/412 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458050
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	11	10.900