DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and CG14205

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_608323.1	Gene:	CG14205 / 32952	FlyBaseID:	FBgn0031034	Length:	713	Species:	Drosophila melanogaster

Alignment Length:	719	Identity:	333/719 - (46%)
Similarity:	459/719 - (63%)	Gaps:	66/719 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TNQVIVFLLCGFVIISA--------------GNPNSDDVLPQFRNVRQLRSLGIEFTEYFRNIST 52
            |..::..|:....:.||              |||....  ..:..:.:||.|.:||...::||:.
  Fly     6 TGPIVSLLVMSLALTSASIRVEHPKNSTLNVGNPEWQS--QSYHTISRLRRLAVEFFAQYQNITI 68

  Fly    53 QDL-GGLESQFSSEDDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPSGLLAGNSYDLGNFDEC 116
            .|| ...|.:..:.|||.||.|::.|...:...:.|||:|||:||:.|||:|.||..||||||||
  Fly    69 SDLYRDKEIRLPTTDDLRCLADLQTLAKDVSDRKLWALRMIDSWGTFPSGILYGNVIDLGNFDEC 133

  Fly   117 LNIRKEIGQERTIQGKYCFLSVSPAKILGIETSIGSF---RTATCFPASCSAINMNAFVDQLMMK 178
            |.|...:.....:|||||...      |.:.:||.:|   :||.||||||||.:|:..:.:|:..
  Fly   134 LGIDHAVTSTHNVQGKYCLSK------LQLASSIPTFLALKTAVCFPASCSADHMDTMLRRLLQN 192

  Fly   179 LLNVSVPSSAMRISEGSCQTSDSEPWDALTIFMIVILSLMSFIVALSTLWDYFLVKDQDQLPAIV 243
            ||::.:......:|||:|:|:|.||:||||||.||:||::..::.|:|:.||.:.:|...|...:
  Fly   193 LLSIELNPDVPLVSEGTCKTADREPYDALTIFTIVVLSILCVLMVLATVCDYLVCQDDQPLNKWI 257

  Fly   244 KICSARSNSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEK 308
            |..|||:|.|.|||:|...|||||||||||||.:|.|||:..|.|.|:...|::||.:..||...
  Fly   258 KAFSARANCRILFRLVAPRSNPNVIDCLHGIRVLSFIWVVYGHIYLVSFFGPNMNLVKLDTWRRS 322

  Fly   309 PFASFILHGFISVDSFLVIGGLLVALIPLRLMDKTKGKLNVPMMYLHRLIRIAPLLAMAIVVHMK 373
            |::..:.|...|||:|..:.|||:.:|.||.|::|||||||.:|||||.:|:.|:||:||:|:|.
  Fly   323 PYSMLVQHAAYSVDTFFFLSGLLMVVIALRAMERTKGKLNVSLMYLHRYLRLTPVLALAIIVYMS 387

  Fly   374 LMPLISSGPLFVGGYIG---NSACKAGWYWTLLFVNNY-TDAKCLAQSWYLSLDMQLYIISPILL 434
            ::|.:..|||:  |.:.   .|.||..||||||:|.|| ||..||..||||::|||||||:||||
  Fly   388 ILPRMGDGPLY--GKVNFDDYSKCKDTWYWTLLYVQNYATDEICLGHSWYLAVDMQLYIIAPILL 450

  Fly   435 ISLYKWGKKAAAGIFILIILLSACLFATMMVNGYSMMITAASPEAMRDGYYATHTHATPWLIGFL 499
            |.||||||||||||.:.::||:||||:.|::...|::  |.|..||...|::|||.|:|:|||.|
  Fly   451 ICLYKWGKKAAAGILVAMLLLAACLFSIMVIGDVSLI--AISEGAMEKIYFSTHTRASPYLIGIL 513

  Fly   500 FGYFLHLNRGKKFQLSWVSVWSGWILCLAMIFTSIFALY--------PPSKWSDPDASTLAESFY 556
            ||||||:||||.|:||.::|..||:..||::|:.:||:|        ||         .:.|:||
  Fly   514 FGYFLHVNRGKSFKLSPITVVLGWLTSLALLFSCLFAVYGYAADAEIPP---------IVEEAFY 569

  Fly   557 YTLTRVGWALALCWVIFACVQGYGGLANSFLASPLWQPLSRLSYSVFIWHMFFMEMNARSTRTST 621
            .|.||:.|.|.||||:|||:.||||||||||:||||||||:||||.:|:|||...:||..|||:|
  Fly   570 LTFTRIAWPLGLCWVVFACMHGYGGLANSFLSSPLWQPLSKLSYSAYIFHMFMESLNAGITRTNT 634

  Fly   622 YFSDYGMMLNFWSTLGFTLLFSYAMHLLIEAPIGGLDIFLRPKGKISPTEKQTSHIDDKEPRDPE 686
            |||||.:||.||...|||:|.::|:::|||||.|.|:..|.|               ||.|..|.
  Fly   635 YFSDYQVMLRFWCDFGFTVLLAFAVYILIEAPFGNLEGLLLP---------------DKRPCPPR 684

  Fly   687 NLLE 690
            ..:|
  Fly   685 PAVE 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	51/115 (44%)
		Acyl_transf_3	268..648	CDD:280013	209/391 (53%)
		OafA	299..654	CDD:224748	196/366 (54%)
CG14205	NP_608323.1	NRF	102..212	CDD:214781	51/115 (44%)
		OafA	269..667	CDD:224748	222/410 (54%)
		Acyl_transf_3	282..660	CDD:280013	209/390 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458051
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	12	11.800