DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-32

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	733	Identity:	190/733 - (25%)
Similarity:	308/733 - (42%)	Gaps:	168/733 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 ISTQDLGGLESQFSSEDDLLCLNDMKALMTGLGSAE--------------------------YWA 88
            |..:.|..|.:|        ||||..   |.:.|.|                          .:|
Worm    27 IKPKPLDNLSAQ--------CLNDTN---TWINSLEIFGTLYAECIIMKKCNAKELKVLRDNLYA 80

  Fly    89 LKMIDAWGSIP-SGLLAGNS-YDLGNFDECLNIRKEIGQERTIQGK-----YCFLSVSPAKILGI 146
            ::.:||:|..| :|||...: || |::.||          :.:.||     ||:|.::|.|.:..
Worm    81 VQQLDAFGQFPGAGLLELKTLYD-GSYQEC----------QRVSGKKYDVNYCYLLLTPGKNVSS 134

  Fly   147 ETSIGS--------FRTATCFPASCSAINMNAFVDQLMMKLLNVSVPSSAMRISEGSCQTSDSEP 203
            .....|        .|.|.|.|.||:..:|....::|.      ..|.:|........:.....|
Worm   135 CAPSNSKSLYSQLPLRIAVCLPDSCNHQDMIDIFNELS------PYPFTACSAYCTKNEVKKDTP 193

  Fly   204 WDALTIFMIVILSLMSFIVALSTLWDY-----FLVKDQDQLPAIVKIC---SARSNSRALFRVVE 260
            :...:||:||    |..|.|::::.||     :.:..|.:.....||.   |..:|:..|..|.|
Worm   194 FWGFSIFLIV----MVVIAAIASIVDYVRETVYGLSSQKENNTFFKILLTFSLWTNAELLLSVKE 254

  Fly   261 SHSN-PNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEKPFASF--------ILH 316
            ..|. ...:||   ||.:|:.||:|.|.:...:::..:          :|...|        :|:
Worm   255 QKSGFIKSLDC---IRLLSMCWVVTGHSFLYLILADTL----------EPVLDFPTYFWNHLLLN 306

  Fly   317 GFISVDSFLVIGGLLVALIPLRLMDKTKGKLNVPM----MYLHRLIRIAPLLAMAIVVHMKLMPL 377
            .|:|||:|.|:.|::||.:..: ...||..:..||    .|:||.:|:.|.:.:.|.......|.
Worm   307 AFVSVDTFFVLSGIVVAYLFFK-TKLTKKTITSPMTWILFYVHRYLRLTPPVMLFIGFFTVYTPY 370

  Fly   378 ISSGPLFVGGYIGN-----SACKAGWYWTLLFVNNYTD-----AKCLAQSWYLSLDMQLYIISPI 432
            |...  |....:..     :|||..|:..||::||:.|     :.|...:|||::|.|||:::||
Worm   371 IQGA--FSASELNQMAPQAAACKTLWWQNLLYINNFDDGNSQNSTCYGITWYLAVDTQLYLVAPI 433

  Fly   433 LLISLYKWGKKAAAGIFILI------ILLSACLF------ATMMVNGYSMMITAASPEAMRDGYY 485
            :|::||   ...|||..|::      |:.:..||      |.::.||       ...:.....|.
Worm   434 VLVALY---FSFAAGTAIIVAGCVGSIITTYILFGVYNVPADIIGNG-------DQTKFFNIAYS 488

  Fly   486 ATHTHATPWLIGFLFGYFLHLNRGKKFQLSWVSVWSGWILCLAMIFTSIFALYPPSK---WSDPD 547
            .......|:|:|.|.||.|.....:|.:|:|....:|||....:....:||.|...|   |
Worm   489 KPWIRCPPYLVGLLTGYLLATYGSRKIRLNWALAIAGWITAFVIAGFCLFATYDYDKGAHW---- 549

  Fly   548 ASTLAESFYYTLTRVGWALALCWVIFACVQGYGGLANSFLASPLWQPLSRLSYSVFI--WHMFFM 610
             ||...:.:|...|:||.:.:|||:.|...|:||..:.|::.|:|||..||||..:|  |.:.:.
Worm   550 -STFTRATFYNFHRLGWGVFVCWVVGANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMVLYY 613

  Fly   611 EMN-------ARSTRTSTYFSDYGMMLN-----FWSTLGFTLLFSYAMHLLIEAPIGGLDIFLRP 663
            .:|       :.:.:..||.:....:|:     |||.| |.:.......:|||..|||..   |.
Worm   614 YLNVGGVLHYSSAWQVFTYIAIPATLLSYVLAFFWSCL-FEVPILKLEKMLIEKLIGGGG---RT 674

  Fly   664 KGKISPTEKQTSHIDDKE 681
            ..|:....|....:.|:|
Worm   675 SLKVEDLGKNIGKVPDEE 692

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	32/153 (21%)
		Acyl_transf_3	268..648	CDD:280013	118/430 (27%)
		OafA	299..654	CDD:224748	112/405 (28%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	31/124 (25%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	120/436 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730