DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-20

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_507007.3	Gene:	oac-20 / 185375	WormBaseID:	WBGene00009488	Length:	719	Species:	Caenorhabditis elegans

Alignment Length:	759	Identity:	205/759 - (27%)
Similarity:	335/759 - (44%)	Gaps:	147/759 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLLCGFVIISAGN-----------------PNSDDVLPQFRNVRQ--LRSLGIEFTEYFRNISTQ 53
            ||:....:|..||                 .|...|.||..|..:  |.||.| .||    :|.:
Worm     3 FLISFLFLIQLGNYFANAKEWKETLLLHHSKNLTGVNPQCNNDTETWLHSLDI-LTE----VSLE 62

  Fly    54 DLGGLESQFSSEDDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPS-GLLAGNSYDLGNFDECL 117
            .:  |..:.|.:::|| |.|           .::||:.:|::|..|| ||........|::.||.
Worm    63 CI--LSKKCSKKEELL-LRD-----------NFYALEQLDSFGKFPSIGLFEVPLIFDGSYQECE 113

  Fly   118 NIRKEIGQERTIQGKYCFLSVSPAKILG--IETSIGS-------FRTATCFPASCSAINMNAFVD 173
            .|..:  .|...:..||::.:.|.|...  .||..|.       ||:|.|.|.||:...::..::
Worm   114 RISGK--SETKYETNYCYVLLIPGKNSSHCHETKSGDLSPTTLFFRSAVCMPNSCNQREISDIIN 176

  Fly   174 QLMMKLLNVSVPSSAMRISEGSCQTSDSEPWDALTIFMIVILSLMSFIVALSTLWDYFL---VKD 235
            ::.      .:|.:|......|.....:..:...::||||::|    |..|:|..||.|   ..|
Worm   177 EIS------DIPFTACGSQCSSYPVEKNSAFWGFSVFMIVMIS----IAILATSVDYILDAIATD 231

  Fly   236 QDQ--------LPAIVKICSARSNSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQYSVTL 292
            ::|        |..|:...|..:|:..:..|.|  .....|.||..||.:|::||::.|..| .:
Worm   232 EEQREKNKRHLLLKILISFSLWTNAELILSVKE--QKVGFIKCLDCIRFLSMLWVVSGHTVS-NI 293

  Fly   293 ISPHINLFRAATWVEKPFASFILHGFISVDSFLVIGGLLVALIPLRLMDKT---KGKLNVPMMYL 354
            :.|.: |....|:.:..:...:|:.|:|||:|.::.|::|:.:..:...|:   |..|...:.|:
Worm   294 MFPDV-LLPVTTFTKHFWNHLLLNAFVSVDTFFLLSGIVVSYLFFKNRMKSSQIKSPLTWILFYV 357

  Fly   355 HRLIRIAPLLAMAI---VVHMKLMPLISSGPLFVGGYIGNSA------CKAGWYWTLLFVNNYTD 410
            ||.:|:.|...:.:   :|:.:.:    .||....|.  |:|      ||..|:..||::||:.|
Worm   358 HRYLRLTPPYMIFLGFYIVYSEYV----QGPTAAAGL--NAAIYSVESCKKTWWRNLLYINNFGD 416

  Fly   411 A--KCLAQSWYLSLDMQLYIISPILLISL---YKWGKKA----AAGIFILIILLSACLFATMMVN 466
            :  .|.|.:|||::|.|||:|:||:||:|   :.||..|    .||..:.:.:|.|
Worm   417 STHACYAITWYLAVDTQLYLIAPIVLIALWFSFVWGALAVAAGCAGSIVTVYVLYA--------- 472

  Fly   467 GYSMMITAASPEAMRDG----YYATHTHATPWLIGFLFGYFLHLNRGKKFQLSWVSVWSGWILCL 527
            .|.:........::.|.    |.......||:|||.|.||.|.:...::.:|.|.....||::..
Worm   473 EYHLPADQFGKGSLLDFGKILYQKPWVRCTPYLIGLLVGYGLAVFGKRRVRLHWALAVVGWLIAF 537

  Fly   528 AMIFTSIFALYPPSK---WSDPDASTLAESFYYTLTRVGWALALCWVIFACVQGYGGLANSFLAS 589
            .:....:|:.....|   |||.:.:|     ||..:|..||:|:.|||.|...|:||..|:|::.
Worm   538 GIAVACLFSTNDYDKGAVWSDFEKAT-----YYNFSRFFWAIAVSWVIVANHMGWGGPINNFMSH 597

  Fly   590 PLWQPLSRLSYSVFIWHMFFMEMNAR-STRTSTYFSDYGMMLN--------------FWSTLGFT 639
            |:|||..:|||..:|.|.|.:..... |.....|:|.:.:.:.              |||.| |.
Worm   598 PIWQPFGKLSYCAYIVHFFLISWYTNISEAPMHYYSTFQVWIYYAVPVTIIAYIFAFFWSCL-FE 661

  Fly   640 LLFSYAMHLLIEAPIGGLDIFLRPKGKISPTEKQTSHIDDKEPR 683
            :.......:||||.:|.  ...|..||:...||..      |||
Worm   662 IPTLKLEKMLIEAILGA--GHTRASGKVGELEKPV------EPR 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	30/122 (25%)
		Acyl_transf_3	268..648	CDD:280013	120/422 (28%)
		OafA	299..654	CDD:224748	113/397 (28%)
oac-20	NP_507007.3	NRF	80..192	CDD:214781	29/119 (24%)
oac-20	NP_507007.3	Acyl_transf_3	270..654	CDD:376607	115/405 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730