DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-7

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_507120.3	Gene:	oac-7 / 180096	WormBaseID:	WBGene00007835	Length:	702	Species:	Caenorhabditis elegans

Alignment Length:	692	Identity:	184/692 - (26%)
Similarity:	310/692 - (44%)	Gaps:	146/692 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 LESQFSS----EDDLLCLNDMKALMTGLG-----------------------SAEYWALKMIDAW 95
            |:|:.:|    |.:..|.||.:..:..|.                       ...::|::.:||:
Worm    29 LKSENASNSLNEVNAQCANDTRTWLQSLKLVAEVSVDCLISRKCNKKEIQIIKDNFYAIEQLDAF 93

  Fly    96 GSIP-SGLLAGNSYDLGNFDECLNIRKEIGQERTIQGK-----YCFLSVSPAKILGIETSIGS-- 152
            |.:| ||:........|::.||          :.|.||     ||:|.:.|.:  ....|||.
Worm    94 GKLPSSGIFEVPLIFDGSYQEC----------QRISGKKYETNYCYLVLVPGR--NSSCSIGGGG 146

  Fly   153 --------FRTATCFPASCSAINMNAFVDQL-MMKLLNVSVPSSAMRISEGSCQTSDSEPWDALT 208
                    ||:|||...||::.::....:|| :|.....:...|:..:.:      ||..| ..:
Worm   147 GFLPSAAFFRSATCMSVSCTSEDLPQLFNQLPLMPFTACAAFCSSFPVEK------DSAFW-GFS 204

  Fly   209 IFMIVILSLMSFIVALSTLWDYF--LVKDQDQLP----AIVKIC---SARSNSRALFRVVESHSN 264
            .||.|::|    |:.|:|..||.  .:|::...|    .|:|:.   |..:|:..|..|.|  ..
Worm   205 AFMCVMIS----ILVLATFIDYLKDAMKNEHSPPPQPNLIMKMLLTFSLWTNAGVLLSVKE--QK 263

  Fly   265 PNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEKPFASFILHGFISVDSFLVIGG 329
            |..|.||..||.:|::||:|.|.:  |.:.|...|...:.:.:..:...:|:.|:|||:|.::.|
Worm   264 PGFIKCLDCIRFLSMLWVVTGHTF--TFVIPPDTLLSMSHFTDHFWNHLLLNAFVSVDTFFLLSG 326

  Fly   330 LLVALIPLRLMDKT---KGKLNVPMMYLHRLIRIAPLLAMAI---VVHMKLMPLISSGPLFVGGY 388
            ::||.:..:...|:   |..|...:.|:||.:|:.|...:.|   :|:.|.:    .||.....:
Worm   327 IVVAYLFFKQKHKSSQIKSPLTWIIFYMHRYLRLTPPYMIFIGFYIVYGKYV----QGPFSASQF 387

  Fly   389 ----IGNSACKAGWYWTLLFVNNYTDAK--CLAQSWYLSLDMQLYIISPILLISLYK---WGKKA 444
                ...:.|::.|:..|.::||..|:.  |.|.||||::|.||||.:||:|:.||.   .|...
Worm   388 NTLLSSIATCESYWWKNLFYINNMGDSSTACYAPSWYLAVDTQLYIFAPIILVGLYYSAIIGSSL 452

  Fly   445 AA----GIFILIILLSAC--LFATMMVNG-----YSMMITAASPEAMRDGYYATHTHATPWLIGF 498
            .|    |..:.:.:|.:.  |.|....||     |.|:            |:.......|:|||.
Worm   453 IAVGMIGSLVTVYILYSIYDLPADFFGNGNTNLLYDMI------------YHKPWIRCPPYLIGL 505

  Fly   499 LFGYFLHLNRGKKFQLSWVSVWSGWILCLAMIFTSIFALYPPSK---WSDPDASTLAESFYYTLT 560
            |.||.|.:...:|.::.|.....||::...:....:|:.|...|   |     |..|.:.||..:
Worm   506 LIGYGLAVFGQRKIRIHWFLAVIGWLVAFGLGMACMFSTYDYDKGAYW-----SIFARATYYNFS 565

  Fly   561 RVGWALALCWVIFACVQGYGGLANSFLASPLWQPLSRLSYSVFIWHMF----FMEMNARST---- 617
            |:.|::|:.|||.|...|:||..::|::.|:||||.||||..:|.|.|    ::.:|..|.
Worm   566 RIAWSIAVSWVIVANHMGWGGPIDAFMSHPMWQPLGRLSYCAYIVHFFTLFWYLNINDSSMHFYS 630

  Fly   618 --RTSTYFSDYGMMLN-----FWSTLGFTLLFSYAMHLLIEA 652
              :...|::....:|:     |||:| |.:.......::|||
Worm   631 TFQVFIYYAVPACLLSYIFAFFWSSL-FEIPILKLKKMMIEA 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	31/129 (24%)
		Acyl_transf_3	268..648	CDD:280013	120/423 (28%)
		OafA	299..654	CDD:224748	111/398 (28%)
oac-7	NP_507120.3	NRF	83..191	CDD:214781	30/119 (25%)
oac-7	NP_507120.3	OafA	261..666	CDD:224748	122/430 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730